{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:16:58Z","timestamp":1788445018020,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,10]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG\u2010AP) patients undergoing double filtration plasmapheresis (DFPP).<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective analysis of 82 HTG\u2010AP\u2010interpreted patients from January 2019 to April 2024 compared target plasma volume treated between up\u2010to\u2010scratch and non\u2010scratch groups. The group comparison used independent samples\n t<\/jats:italic>\n \u2010test, Mann\u2013Whitney\n U<\/jats:italic>\n \u2010test, and chi\u2010square test. Binary logistic regression was used to identify independent risk factors for patients' plasma volume target failure. The ROC curve assessed these risk factors' diagnostic efficacy.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 82 patients, 52 were classified as belonging to the up\u2010to\u2010scratch group, while the remaining 30 were classified as belonging to the non\u2010to\u2010scratch group. Statistically significant differences were seen between the groups regarding admission heart rate, triglyceride, calcitonin gene, C\u2010reactive protein, D\u2010dimer, and fibrinogen (FIB) levels (\n p<\/jats:italic>\n <0.05). The binary logistic regression analysis showed that for every 1\u2009mmol\/L increase in triglycerides (TG), the probability of experiencing substandard target plasma handling increased by 5.0% (OR\u2009=\u20091.05, 95%CI 1.01\u20131.08,\n p<\/jats:italic>\n \u2009=\u20090.009). Furthermore, for each g\/L rise in FIB, there was a 74% increase in the likelihood of encountering suboptimal target plasma handling (OR\u2009=\u20091.74, 95%CI 1.18\u20132.56,\n p<\/jats:italic>\n \u2009=\u20090.005). The ROC curve study revealed that the AUC for TG was 0.67, for FIB was 0.77, and for the combination of both markers was 0.80; all the\n p<\/jats:italic>\n values were below 0.05.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The increased levels of TG and FIB are independent risk factors affecting the target plasma handling achievement rate in HTG\u2010AP patients undergoing DFPP.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1744-9987.14232","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T19:23:13Z","timestamp":1732562593000},"page":"690-697","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis"],"prefix":"10.1111","volume":"30","author":[{"given":"Hui","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine The First People's Hospital of Linping District Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenqiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine The First People's Hospital of Linping District Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1869-8788","authenticated-orcid":false,"given":"Yunlong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine The First People's Hospital of Linping District Hangzhou 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Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.14232","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1744-9987.14232","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.14232","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T13:47:37Z","timestamp":1788443257000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.14232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,25]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/1744-9987.14232"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.14232","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,25]]},"assertion":[{"value":"2024-07-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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