{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:37:29Z","timestamp":1792028249650,"version":"4.4.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T00:00:00Z","timestamp":1735776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T00:00:00Z","timestamp":1735776000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The objective of this study is to investigate the dynamic changes in serum albumin and ferritin as potential predictors for early\u2010onset peritoneal dialysis\u2010related peritonitis (PDRP) in patients undergoing peritoneal dialysis (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included 215 patients with end\u2010stage renal disease who initiated PD at Huadong Hospital. Patients were followed up to 24\u2009months, during which episodes of PDRP were recorded. The dynamic changes in serum albumin and ferritin levels were evaluated within the first 6\u2009months of PD initiation. Data were analyzed to assess the relationship between these biomarkers and early\u2010onset PDRP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 215 patients, 33.49% developed PDRP, and 28.93% experienced early\u2010onset PDRP. Patients with lower baseline serum albumin levels (&lt;35\u2009g\/L) and higher baseline ferritin levels (\u2265400\u2009\u03bcg\/L) had an increased risk of developing early\u2010onset PDRP. Importantly, the risk associated with low initial albumin was not significant when serum albumin levels remained stable within the first 6\u2009months (\u22125% to 5% change). Similarly, although higher baseline ferritin was associated with a higher risk of early\u2010onset PDRP, patients with fluctuating ferritin levels (more than 35% change) showed no significant increase in the risk. Kaplan\u2013Meier analysis revealed a lower cumulative technical survival rate in patients with early\u2010onset PDRP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dynamic changes in serum albumin and ferritin levels within the first 6\u2009months of PD can serve as significant predictors of early\u2010onset PDRP, but stable levels of these markers mitigate their predictive value. Close monitoring of these biomarkers may help in identifying high\u2010risk patients and improving PD outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1744-9987.14244","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T02:26:27Z","timestamp":1735871187000},"page":"731-738","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dynamic changes in serum albumin and ferritin indicate higher risk of early\u2010onset peritonitis in peritoneal dialysis patients"],"prefix":"10.1111","volume":"30","author":[{"given":"Jinqing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Nephrology Huadong Hospital, Fudan University  Shanghai China"},{"name":"Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital, Fudan University  Shanghai 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