{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:10:10Z","timestamp":1746403810489,"version":"3.40.4"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T00:00:00Z","timestamp":1738540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Serum potassium levels &lt;3\u2009mEq\/L at post\u2010hemodialysis (HD) are closely associated with poor prognosis. This study aimed to identify high\u2010risk patients with post\u2010HD hypokalemia after regular HD using potassium (2\u2009mEq\/L) dialysate solution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 129 patients receiving HD and 1121 HD sessions were enrolled in this single\u2010center retrospective cross\u2010sectional study. The association of post\u2010HD hypokalemia less than 3\u2009mEq\/L with patient background, as well as each dialysis session was investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Approximately 16% of 129 patients and 10% of 1121 sessions showed post\u2010HD hypokalemia. In per\u2010patient analysis, more inpatients and lower dry weight were found in the hypokalemia group compared with the non\u2010hypokalemia group. Logistic regression analysis indicated that lower dry weight was significantly associated with higher risk of hypokalemia independent of inpatients (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). To determine the best cut\u2010off value of pre\u2010HD potassium for identifying post\u2010HD hypokalemia, receiver operating curve analysis was performed in per\u2010session analysis. The results showed that the optimal pre\u2010HD potassium cut\u2010off value was 4.2\u2009mEq\/L. In the 250 sessions below the optimal cut\u2010off value for post\u2010HD hypokalemia development, 28.8% of sessions with potassium correction showed post\u2010HD hypokalemia, compared to 40.8% of sessions without potassium correction. Although numerically lower, the difference did not reach statistical significance (<jats:italic>p<\/jats:italic>\u2009=\u20090.125).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results indicated that a relatively lower dry weight was more likely to complicate post\u2010HD hypokalemia. Potassium supplementation for high\u2010risk patients during HD sessions may be needed to prevent post\u2010HD hypokalemia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.14256","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T03:10:31Z","timestamp":1738638631000},"page":"365-374","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lower dry weight is associated with post\u2010hemodialysis hypokalemia"],"prefix":"10.1111","volume":"29","author":[{"given":"Daigo","family":"Sunagawa","sequence":"first","affiliation":[{"name":"Division of Dialysis Center Nissan Tamagawa Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7387-8066","authenticated-orcid":false,"given":"Yoshihiko","family":"Imamura","sequence":"additional","affiliation":[{"name":"Division of Dialysis Center Nissan Tamagawa Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeko","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Division of Dialysis Center Nissan Tamagawa Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromitsu","family":"Inoue","sequence":"additional","affiliation":[{"name":"Division of Dialysis Center Nissan Tamagawa Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayato","family":"Wakabayashi","sequence":"additional","affiliation":[{"name":"Division of Dialysis Center Nissan Tamagawa Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihide","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Division of Dialysis Center Nissan Tamagawa Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasunori","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Division of 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