{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:11:55Z","timestamp":1767006715496,"version":"3.40.4"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aimed to investigate the effect of intermittent hemodialysis filtration mode (<jats:styled-content style=\"fixed-case\">IHDF<\/jats:styled-content>) on intradialytic hypotension and nutritional status in patients with end\u2010stage renal disease (<jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content> who underwent hemodialysis and were treated at our hospital from December 2021 to December 2023 according to the inclusion and exclusion criteria were selected and randomly assigned into two groups: the experimental group (patients received intermittent hemodialysis filtration mode treatment, <jats:italic>n<\/jats:italic>\u2009=\u200950) and the control group (patients received conventional maintenance hemodialysis treatment, <jats:italic>n<\/jats:italic>\u2009=\u200949). Subsequently, the participant characteristics, the treatment effect, the occurrence of intradialytic hypotension, the safety assessment, blood pressure indicators, and the nutritional status were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to the control group, the experimental group had a better treatment effect, a lower incidence of hypotension, a lower rate of complications, and higher levels of albumin (<jats:styled-content style=\"fixed-case\">ALB<\/jats:styled-content>), hemoglobin (Hb), prealbumin (<jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>), transferrin (<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>), diastolic blood pressure (<jats:styled-content style=\"fixed-case\">DBP<\/jats:styled-content>), systolic blood pressure (<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>), and mean arterial pressure (<jats:styled-content style=\"fixed-case\">MAP<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">IHDF<\/jats:styled-content> could effectively improve the therapeutic effect of patients with <jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content>, reduce the incidence of hypotension during dialysis, regulate blood pressure balance, maintain the nutritional level of patients, decrease the occurrence of complications, and have higher safety.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.70005","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T09:09:26Z","timestamp":1741856966000},"page":"375-386","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of intermittent hemodialysis filtration mode on intradialytic hypotension and nutritional status in patients with end\u2010stage renal disease"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8117-346X","authenticated-orcid":false,"given":"Meina","family":"Guo","sequence":"first","affiliation":[{"name":"Nephrology Blood Purification Center The First Medical Center, Chinese People's Liberation Army General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Long","sequence":"additional","affiliation":[{"name":"Nephrology Blood Purification Center The First Medical Center, Chinese People's Liberation Army General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[{"name":"Nephrology Blood Purification Center The First Medical Center, Chinese People's Liberation Army General Hospital  Beijing 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