{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:39:25Z","timestamp":1782819565687,"version":"3.54.5"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Given that social frailty is closely associated with adverse health outcomes among older maintenance hemodialysis (\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      ) patients, this study aimed to investigate the prevalence of social frailty among older\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      patients, with an emphasis on its correlation with factors such as family functioning, self\u2010care ability, depression, and physical frailty.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A multi\u2010center cross\u2010sectional investigation was conducted to recruit older patients with\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      between September and December 2024 from four hemodialysis centers in four tertiary hospitals in Sichuan Province, China. Self\u2010report scales were employed to collect general information and assess the participants\u2019 social frailty, family functioning, depression, and physical frailty. Univariate analysis and binary logistic regression analysis were adopted to determine the predictors of social frailty.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 386 older\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      patients were included in the analysis. Of the participants, 205 (53.1%) were diagnosed with social frailty. Binary logistic regression analyses demonstrated that family functioning (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u2009=\u20090.863, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 0.776\u20130.960,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007), self\u2010care ability (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u2009=\u20093.527, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.958\u20136.352,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), depression (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u2009=\u20092.007, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.180\u20133.415,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010), and physical frailty (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u2009=\u20092.261, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.237\u20134.133,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008) were significantly associated with social frailty among older\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Social frailty is highly prevalent among older patients with\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      . In addition, family function, self\u2010care ability, depression, and physical frailty were detected to be independently associated with social frailty. These findings could facilitate the refinement of daily care strategies for older patients with\n                      <jats:styled-content style=\"fixed-case\">MHD<\/jats:styled-content>\n                      to reduce or mitigate the negative effects of social frailty.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1744-9987.70070","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:40:04Z","timestamp":1754527204000},"page":"878-884","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and Associated Factors of Social Frailty in Older Patients on Maintenance Hemodialysis: A Multi\u2010Centre Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1511-8128","authenticated-orcid":false,"given":"Qin","family":"Zhang","sequence":"first","affiliation":[{"name":"Hemodialysis Center, Department of Nephrology West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1894-6736","authenticated-orcid":false,"given":"Xu\u2010Hua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Hemodialysis Center, Department of Nephrology West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Hemodialysis Center, Department of Nephrology West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University  Chengdu Sichuan 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