{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:45:38Z","timestamp":1790653538551,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This pioneering study aimed to examine the effects of virtual reality (VR)\u2010based videos on symptoms, vital signs, and comfort levels in hemodialysis patients, offering an innovative approach to improving their quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This randomized controlled pretest\u2010posttest study included 54 hemodialysis patients treated at \u201cX\u201d Hospital between June 2024 and May 2025. Twenty\u2010five patients were assigned to the intervention group, 25 to the control group, and 4 to a pilot group. Data were collected at baseline and after 8\u2009weeks. Statistical analyses included\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests, repeated measures ANOVA, Mann\u2013Whitney U, and Friedman tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the intervention group, Dialysis Symptom Index (DSI)\u00a0scores decreased significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and comfort levels increased significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) across all subscales of the Hemodialysis Comfort Scale Version II. Vital signs remained within normal ranges before and after the intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study revealed that the use of virtual reality headsets significantly influenced dialysis symptom index scores and comfort levels. The intervention effectively reduced dialysis symptoms and significantly increased patient comfort. No significant differences were observed in vital signs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1744-9987.70092","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T09:21:02Z","timestamp":1761816062000},"page":"59-67","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Determination of the Effects of Virtual Reality\u2010Based Videos on Symptoms, Vital Signs and Comfort in Hemodialysis Patients"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3567-6057","authenticated-orcid":false,"given":"Dilan Aktepe","family":"Co\u015far","sequence":"first","affiliation":[{"name":"Department of Medical Services and Techniques Gumushane University  Gumushane Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2037-0060","authenticated-orcid":false,"given":"Nuray","family":"Bing\u00f6l","sequence":"additional","affiliation":[{"name":"\u0130nternal Medicine Nursing Department, Faculty of Nursing Atat\u00fcrk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2022.09.032"},{"key":"e_1_2_10_3_1","first-page":"103","volume-title":"Handbook for Dialysis Technicians","author":"Yurgen B.","year":"2015"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882\u2010023\u201003176\u2010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2024.2411367"},{"issue":"2","key":"e_1_2_10_6_1","first-page":"70","article-title":"Ensuring Comfort in Patients Receiving Hemodialysis Treatment","volume":"7","author":"\u015eahin C. K.","year":"2021","journal-title":"Turkiye Klinikleri Internal Medicine Nursing\u2010Special Topics"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.31125\/hunhemsire.763155"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.10.016"},{"key":"e_1_2_10_9_1","unstructured":"E.Ay \u201cThe Effect of Breathing and Cough Exercises Performed With Virtual Reality on Self\u2010Efficacy and Quality of Life in COPD Patients\u201d (doctoral thesis Atat\u00fcrk University 2023) https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/."},{"key":"e_1_2_10_10_1","first-page":"164","article-title":"Virtual Health: An Overview of Virtual Reality in Health","volume":"32","author":"\u00d6zt\u00fcrk E. O.","year":"2020","journal-title":"Kocaeli \u00dcniversitesi Fen Bilimleri Dergisi"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apnr.2024.15184"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0005522020"},{"key":"e_1_2_10_13_1","unstructured":"E.Bulut \u201cEvaluation of the Effects of Virtual Reality Glasses and Respiratory Exercise Applications on Symptoms and Quality of Life in Patients Receiving Hemodialysis Treatment\u201d (doctoral thesis Trakya University 2024) https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/."},{"key":"e_1_2_10_14_1","unstructured":"S.G\u00fclp\u0131nar \u201cInvestigation of the Effects of Foot Massage and Virtual Reality Applications on Hemodialysis Symptoms and Comfort Level\u201d (Doctoral thesis Karadeniz Technical University National Thesis Center 2025) https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/."},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.47565\/ndthdt.2020.2"},{"key":"e_1_2_10_16_1","unstructured":"M.Yi\u011fit \u201cThe Effect of Virtual Reality Glasses Applied to Hemodialysis Patients on Vital Signs and Anxiety Level\u201d (Master's Thesis Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Y\u00d6K Thesis Center 2025) https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.47565\/ndthdt.2024.83"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.47565\/ndthdt.2024.86"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/SGA0000000000000733"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.5262\/tndt.2013.100108"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/17449871211041834"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.614539"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.2196\/45100"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2020.102488"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2018.0527"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jorc.12362"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2024.11.018"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/237796082093616"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010023\u201039709\u2010y"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2021.03.009"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/11297298231225755"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLE.0000000000001279"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.33808\/clinexphealthsci.14.3.979"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.29422"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534735419871108"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2023.102424"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/frvir.2024.1466362"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.2196\/58384"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102019\u2010033336"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010024\u201009036\u20107"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/CIN.0000000000000953"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijn.13176"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvn.2021.01.001"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2024.05.028"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctcp.2024.101931"},{"key":"e_1_2_10_46_1","unstructured":"B.Y\u0131lmaz \u201cThe Effect of Virtual Reality Glasses on Pain During Hemodialysis Treatment\u201d (Master's Thesis Atat\u00fcrk University Y\u00d6K Thesis Center 2023) https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/."},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctcp.2024.101848"},{"key":"e_1_2_10_48_1","unstructured":"E.\u015eahin \u201cThe Effect of Using Virtual Reality Glasses on Pain and Comfort Levels After Care in Intensive Care Patients\u201d (Master's Thesis \u00c7ank\u0131r\u0131 Karatekin University Y\u00d6K Thesis Center 2024) https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/."}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.70092","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1744-9987.70092","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.70092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:58:38Z","timestamp":1785452318000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.70092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,30]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/1744-9987.70092"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.70092","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,30]]},"assertion":[{"value":"2025-07-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}