{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T03:50:04Z","timestamp":1788234604197,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T00:00:00Z","timestamp":1492732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Integrative Zoology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Kisspeptins and G protein coupled receptor (<jats:italic>GPR54<\/jats:italic>) play significant roles in regulating reproductive activity among seasonally reproductive animals; however, the mechanisms of <jats:italic>KiSS\u20101<\/jats:italic> and <jats:italic>GPR54<\/jats:italic> gene affecting the seasonal reproduction in striped hamster are still unknown. In this study, real\u2010time quantitative polymerase chain reaction was employed to examine the expression profiles of <jats:italic>KiSS\u20101<\/jats:italic> and <jats:italic>GPR54<\/jats:italic> in the hypothalamus, ovaries, testes, uterus and epididymis of striped hamsters across 4 different seasons. Our results showed that, across different seasons, the <jats:italic>KiSS\u20101<\/jats:italic> expression mode of male striped hamsters and the <jats:italic>GPR54<\/jats:italic> expression mode of female striped hamsters were consistent with the seasonal photoperiod in the hypothalamus. Meanwhile, across different seasons, the expression profile of <jats:italic>KiSS\u20101<\/jats:italic> in the testes and the <jats:italic>GPR54<\/jats:italic> expression profile of male striped hamsters in the hypothalamus were consistent with the intensity of their seasonal reproductive activity. Among different tissues, the expression trend for <jats:italic>GPR54<\/jats:italic> is consistent across 4 seasons, while that for <jats:italic>KiSS\u20101<\/jats:italic> is tissue\u2010dependent. The expression trend for <jats:italic>GPR54<\/jats:italic> across 4 seasons is the same regardless of gender, while that for <jats:italic>KiSS\u20101<\/jats:italic> is dramatically different and sex\u2010dependent across different seasons. These results suggest that the expressions of <jats:italic>KiSS\u20101<\/jats:italic> and <jats:italic>GPR54<\/jats:italic> in the striped hamsters were regulated by complicated mechanisms, and the regulatory mechanisms in the striped hamsters are seasonal\u2010dependent and sex\u2010dependent. This research will provide a theoretical basis for studying how <jats:italic>KiSS\u20101<\/jats:italic> and <jats:italic>GPR54<\/jats:italic> affect seasonal reproduction and the mechanisms behind their influence.<\/jats:p>","DOI":"10.1111\/1749-4877.12223","type":"journal-article","created":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T19:00:55Z","timestamp":1472670055000},"page":"260-268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Seasonal differential expression of <i>KiSS\u20101\/GPR54<\/i> in the striped hamsters (<i>Cricetulus barabensis<\/i>) among different tissues"],"prefix":"10.1111","volume":"12","author":[{"given":"Laixiang","family":"XU","sequence":"first","affiliation":[{"name":"College of Life Sciences Qufu Normal University  Qufu Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiliang","family":"XUE","sequence":"additional","affiliation":[{"name":"College 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