{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T17:04:57Z","timestamp":1789405497330,"version":"build-2803163510"},"reference-count":75,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32100341"],"award-info":[{"award-number":["32100341"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Integr. Zool."],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Reproduction in vertebrates usually involves egg\u2010laying (oviparity) or live\u2010bearing (viviparity). Oviparity is the ancestral trait from which viviparity has independently evolved more than 100 times in squamate reptiles. This transition involves a series of physiological and structural changes, including the degeneration of eggshell and the evolution of a placenta and differences in the temporal and spatial expression patterns of some functional genes that drive the structural transformation. Long non\u2010coding RNAs (lncRNAs) play important roles in the regulation of gene expression, yet it remains unclear whether they participate in gene expression shifts during the transition from oviparity to viviparity, and if so how. Therefore, we employ deep mining to identify novel lncRNAs of a closely related oviparous\u2010viviparous pair of lizards (\n                    <jats:italic>Phrynocephalus przewalskii<\/jats:italic>\n                    and\n                    <jats:italic>P. vlangalii<\/jats:italic>\n                    ). We construct cis\u2010 and trans\u2010regulatory networks between lncRNAs and target genes using the transcriptomic data of oviduct or uteri tissues across reproductive periods. Results show that lncRNAs that regulate eggshell gland developmental genes in the oviparous lizard are lost or less expressed in the viviparous lizard. A number of lncRNAs involved in the regulation of placental development and embryo attachment in viviparous species have no orthologs\u00a0in oviparous species, and others show little or no expression. Accordingly, lncRNAs may play important regulatory roles in the physiological and structural changes in the transition from oviparity to viviparity. These results open doors to the further elucidation of genetic regulatory networks.\n                  <\/jats:p>","DOI":"10.1111\/1749-4877.12992","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:20:18Z","timestamp":1745886018000},"page":"1300-1313","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genome\u2010Wide Mining of lncRNAs Reveals Their Potential Regulatory Role in the Evolution of Viviparity"],"prefix":"10.1111","volume":"21","author":[{"given":"Xiaogang","family":"Feng","sequence":"first","affiliation":[{"name":"State Key Laboratory of Genetic Evolution &amp; Animal Models, and Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of Zoology, Chinese Academy of Sciences  Kunming China"},{"name":"Kunming College of Life Science University of Chinese Academy of Sciences  Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Gao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Genetic Evolution &amp; Animal Models, and Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of Zoology, Chinese Academy of Sciences  Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Dong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Genetic Evolution &amp; Animal Models, and Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of Zoology, Chinese Academy of Sciences  Kunming China"},{"name":"Kunming College of Life Science University of Chinese Academy of Sciences  Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijing","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Bio\u2010Resource in Yunnan, School of Life Sciences Yunnan University  Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Murphy","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Genetic Evolution &amp; Animal Models, and Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of Zoology, Chinese Academy of Sciences  Kunming China"},{"name":"Centre for Biodiversity and Conservation Biology Royal Ontario Museum  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaping","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Genetic Evolution &amp; Animal Models, and Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of Zoology, Chinese Academy of Sciences  Kunming China"},{"name":"State Key Laboratory for Conservation and Utilization of Bio\u2010Resource in Yunnan, School of Life Sciences Yunnan University  Kunming China"},{"name":"Southwest United Graduate School  Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Che","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Genetic Evolution &amp; Animal Models, and Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of Zoology, Chinese Academy of Sciences  Kunming China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.10520"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.3907"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.082758ea"},{"key":"e_1_2_8_5_1","first-page":"247","article-title":"Viviparity in Reptiles: Evolution and Reproductive Endocrinology","author":"Albergotti L. 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