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Zool."],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Understanding which mammalian species participate in the sylvatic cycle of\n                    <jats:italic>Trypanosoma cruzi<\/jats:italic>\n                    is vital for clarifying the ecological processes that maintain Chagas disease transmission. Although more than 100 mammal species have been reported as naturally infected, the actual diversity of hosts is much broader. In this study, we employed a trait\u2010based, machine\u2010learning framework to evaluate mammals associated with natural infection. Data concerning life\u2010history traits, morphological characteristics, environmental factors, trophic ecology, habitat use, biogeographic distributions, and spatial overlap with triatomine vectors were compiled to model compatibility with\n                    <jats:italic>T. cruzi<\/jats:italic>\n                    infection using extreme gradient\u2010boosted regression. Our analysis indicates that triatomines overlap with 573 mammal species. While triatomines are considered generalists, they also utilize mammal species with specific traits, such as den\u2010dwelling behavior, medium to large body size, and tolerance to habitat disturbance. This approach offers a structured foundation for identifying potential host species and prioritizing field research in regions that are insufficiently studied. By integrating ecological traits with geographic and behavioral data, the model enhances the understanding of host\u2013parasite interactions in sylvatic Chagas disease and supports targeted surveillance of predicted mammalian hosts.\n                  <\/jats:p>","DOI":"10.1111\/1749-4877.70216","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:29:16Z","timestamp":1792067356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predicting Mammal Species Suitable for Chagas Disease Spread Using a Machine\u2010Learning Framework"],"prefix":"10.1111","author":[{"given":"Maya","family":"Rocha\u2010Ortega","sequence":"first","affiliation":[{"name":"Instituto de Ecolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Coyoac\u00e1n  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carezza","family":"Botto\u2010Mahan","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Ecol\u00f3gicas, Facultad de Ciencias Universidad de Chile  Santiago Chile"},{"name":"Research Ring in Pest Insects and Climatic Change (PIC2) Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Rojo","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Agroalimentarias Animales y Ambientales (ICA3) Universidad de O'Higgins  San Fernando Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5978-1660","authenticated-orcid":false,"given":"Alex","family":"C\u00f3rdoba\u2010Aguilar","sequence":"additional","affiliation":[{"name":"Instituto de Ecolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Coyoac\u00e1n  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2015.07.005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/emph\/eoab009"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2017.05.003"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjh249"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666\u20105247(21)00245\u20107"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/0074\u20100276140048"},{"key":"e_1_2_9_8_1","first-page":"1044","article-title":"Copernicus Global Land Service: Land Cover 100M: Collection 3: Epoch 2015: Globe (Version V3.0.1)","volume":"12","author":"Buchhorn M.","year":"2020","journal-title":"Remote Sensing"},{"key":"e_1_2_9_9_1","first-page":"1","volume-title":"Biology of Trypanosoma cruzi","author":"Buckner C. 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