{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:15:52Z","timestamp":1784898952387,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T00:00:00Z","timestamp":1382054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Alicyclobacillus acidoterrestris<\/jats:italic>\n                    is a gram\u2010positive aerobic bacterium. This bacterium resists pasteurization temperatures and low pH and is usually involved in the spoilage of juices and acidic drinks. The objective of this study was to evaluate the antibacterial activities of nisin and the species\n                    <jats:italic>Piper<\/jats:italic>\n                    (\n                    <jats:italic>Piperaceae<\/jats:italic>\n                    ) on\n                    <jats:italic>A. acidoterrestris<\/jats:italic>\n                    . The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) were determined by the broth microdilution method. The species\n                    <jats:italic>Piper aduncum<\/jats:italic>\n                    had the lowest MIC and an MBC of 15.6 \u03bcg\/mL and was selected for fractionation. Six fractions were obtained, and the dichloromethane fraction (F.3) had the lowest MIC\/MBC (7.81 \u03bcg\/mL). The dichloromethane fraction was again fractionized, and a spectral analysis revealed that the compound was prenylated chromene (F.3.7). The checkerboard method demonstrated that the crude extract (CE) of\n                    <jats:italic>P. aduncum<\/jats:italic>\n                    plus nisin had a synergistic interaction (fractional inhibitory concentration [FIC] = 0.24). The bactericidal activity of (F.3.7) was confirmed by the time\u2013kill curve.\n                    <jats:italic>P. aduncum<\/jats:italic>\n                    , nisin, and prenylated chromene exhibited strong antibacterial activity against the spores and vegetative cells of\n                    <jats:italic>A. acidoterrestris<\/jats:italic>\n                    . The results of this study suggest that extracts of the genus\n                    <jats:italic>Piper<\/jats:italic>\n                    may provide an alternative to the use of thermal processing for controlling\n                    <jats:italic>A<\/jats:italic>\n                    . spoilage.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.12283","type":"journal-article","created":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T13:42:45Z","timestamp":1382103765000},"source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of the Antibacterial Activity of\n                    <i>Piperaceae<\/i>\n                    Extracts and Nisin on\n                    <i>Alicyclobacillus Acidoterrestris<\/i>"],"prefix":"10.1111","volume":"78","author":[{"given":"Suelen P.","family":"Ruiz","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancia de Alimentos, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia Maria dos","family":"Anjos","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancia de Alimentos, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa S.","family":"Carrara","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias Farmac\u00eauticas, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana N.","family":"deLima","sequence":"additional","affiliation":[{"name":"Dept. de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di\u00f3genes Apar\u00edcio G.","family":"Cortez","sequence":"additional","affiliation":[{"name":"Dept. de Farm\u00e1cia e Farmacologia, Maring\u00e1, Brazil  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e2nia U.","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Dept. de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celso V.","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Dept. de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben\u00edcio A.","family":"de Abreu Filho","sequence":"additional","affiliation":[{"name":"Dept. de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Univ  Estadual de Maring\u00e1 Maring\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(99)00132-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.31.538"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.2008.01776.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01041898"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(01)00560-8"},{"key":"e_1_2_7_7_1","volume-title":"Methods for diluition antimicrobial susceptibility tests for bacteria that grow aerobically, approved standard","author":"CLSI (Clinical and Laboratory Standards Institute)","year":"2003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-67-1-9"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0723-2020(87)80009-7"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.1999.00780.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762002000700017"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1472-765X.2001.01008.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2621.1999.00243.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786410601130711"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(97)00828-5"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2006.10.025"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(93)85364-W"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-63.11.1517"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(97)00328-2"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1517-83822009000300024"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762003000800025"},{"key":"e_1_2_7_22_1","first-page":"2260","article-title":"The effect of nisin and garlic (Allium sativum L.) essential oil separately and in combination on the growth of Listeria monocytogenes","volume":"44","author":"Rohani SMR","year":"2011","journal-title":"Food Sci Technol"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2006.03.013"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/bp030013r"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/82.13.1107"},{"key":"e_1_2_7_26_1","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1128\/aem.57.12.3613-3615.1991","article-title":"Nisin treatment for inactivation of Salmonella species and other Gram\u2010negative bacteria","volume":"57","author":"Stevens KA","year":"1991","journal-title":"Appl Environ Microb"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2006000300009"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-65.2.415"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-42-2-263"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2006.03.001"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1006\/fmic.1999.0309"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.60.543"}],"container-title":["Journal of Food Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1750-3841.12283","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ift.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1750-3841.12283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T14:49:12Z","timestamp":1762181352000},"score":1,"resource":{"primary":{"URL":"https:\/\/ift.onlinelibrary.wiley.com\/doi\/10.1111\/1750-3841.12283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,18]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/1750-3841.12283"],"URL":"https:\/\/doi.org\/10.1111\/1750-3841.12283","archive":["Portico"],"relation":{},"ISSN":["0022-1147","1750-3841"],"issn-type":[{"value":"0022-1147","type":"print"},{"value":"1750-3841","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,18]]}}}