{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:55:21Z","timestamp":1791309321826,"version":"4.3.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,12,3]],"date-time":"2014-12-03T00:00:00Z","timestamp":1417564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In this study, supercritical fluid extraction has been successfully applied to a sequential fractionation of fatty acids and polyphenols from wine wastes (2 different\n                    <jats:italic>vitis vinifera<\/jats:italic>\n                    grapes). To this aim, in a 1st step just fatty acids were extracted and in a 2nd one the polyphenols. The variables that affected to the extraction efficiency were separately optimized in both steps following an experimental design approach. The effect of extraction temperature flow, pressure, and time were thoroughly evaluated for the extraction of fatty acids, whereas the addition of methanol was also considered in the case of the polyphenols extraction. A quantitative extraction with high efficiency was achieved at a very short time and low temperatures. Concerning quantification, fatty acids were determined by means of gas chromatography coupled to mass spectrometry after a derivatization step, whereas the polyphenols were analyzed by means of high performance liquid chromatography coupled to tandem mass spectrometry and the Folin\u2013Ciocalteu method.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.12715","type":"journal-article","created":{"date-parts":[[2014,12,4]],"date-time":"2014-12-04T13:59:29Z","timestamp":1417701569000},"source":"Crossref","is-referenced-by-count":43,"title":["Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from\n                    <i>Vitis Vinifera<\/i>\n                    Grape Wastes"],"prefix":"10.1111","volume":"80","author":[{"given":"Oier","family":"Aizpurua\u2010Olaizola","sequence":"first","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markel","family":"Ormazabal","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asier","family":"Vallejo","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maitane","family":"Olivares","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Navarro","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestor","family":"Etxebarria","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aresatz","family":"Usobiaga","sequence":"additional","affiliation":[{"name":"Analytical Chemistry Dept Univ. of the Basque Country (UPV\/EHU)  Barrio Sarriena s\/n 48940 Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1100\/2012\/790486"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(03)01187-7"},{"key":"e_1_2_10_4_1","first-page":"569","volume-title":"Waste management for the food industries","author":"Arvanitoyannis IS","year":"2007"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf030510n"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2003.09.001"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)01051-1"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-398456-2.00016-5"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.08.049"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/np990352n"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathophys.2007.04.001"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-374420-3.00152-2"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2174\/2212798405666131129153239"},{"key":"e_1_2_10_14_1","first-page":"227","article-title":"Recovery of grape seed oil by liquid and supercritical carbon dioxide extraction: a comparison with conventional solvent extraction","volume":"61","author":"G\u00f3mez AM","year":"1996","journal-title":"Chem Eng J"},{"key":"e_1_2_10_15_1","unstructured":"HertogMGL.1994.Flavonols and flavones in foods and their relation with cancer and coronary heart disease risk[PhD thesis].Agricultural Univ. 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