{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:06:51Z","timestamp":1778494011302,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T00:00:00Z","timestamp":1425513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Berries are dietary plants with high antioxidant activity. The aim of this study is to investigate the protective effect of berries (strawberry, grape, and blueberry) against the acrylamide (AA)\u2010induced general toxicity, genotoxicity, and reproductive toxicity in mice model, respectively. Mice were treated with 50 mg\/kg b.w.\/day AA intraperitoneal injection for 5 d after feeding control diet or diet containing freeze\u2010dried strawberry, grape, and blueberry powder. The results showed that AA induced a significant general toxicity, genotoxicity, and reproductive toxicity in mice. Compared with the control diet, the diets containing berries could reverse the AA\u2010induced alterations in liver antioxidant enzymes activities (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). Moreover, the AA\u2010induced genotoxicity could be prevented by the diet containing berries. The DNA damage in the lymphocyte and liver cells and the micronucleus formation in bone marrow cell were significantly alleviated (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). Meanwhile, the mice fed with diets containing berries showed a recovery in the sperm count, the sperm activity rate, sperm motility parameters, and the abnormal sperm rate (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). Berry powders have remarkable intervention against the AA\u2010induced general toxicity, genotoxicity, reproductive toxicity. Abundant phenolics, especially anthocyanins, may contribute to the intervention.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.12815","type":"journal-article","created":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T10:04:44Z","timestamp":1425549884000},"source":"Crossref","is-referenced-by-count":31,"title":["Evaluation of Protective Effect of Freeze\u2010Dried Strawberry, Grape, and Blueberry Powder on Acrylamide Toxicity in Mice"],"prefix":"10.1111","volume":"80","author":[{"given":"Mengyao","family":"Zhao","sequence":"first","affiliation":[{"name":"College of Food Science &amp; Nutritional Engineering, Natl. Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education China Agricultural Univ  Beijing 100083 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Nutritional Engineering, Natl. Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education China Agricultural Univ  Beijing 100083 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghua","family":"Luo","sequence":"additional","affiliation":[{"name":"Dept. of Nutrition and Food Science Univ. of Maryland  College Park MD 20742\u20107640 U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Guo","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Nutritional Engineering, Natl. Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education China Agricultural Univ  Beijing 100083 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaosong","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Nutritional Engineering, Natl. Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education China Agricultural Univ  Beijing 100083 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Nutritional Engineering, Natl. Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education China Agricultural Univ  Beijing 100083 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5718(02)00322-4"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.111.140178"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1218(88)90124-3"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2010.07.004"},{"key":"e_1_2_7_6_1","first-page":"161","article-title":"The effects of oral grape seed extract in cisplatin\u2010induced cytogenotoxicity in mice","volume":"16","author":"Attia SM","year":"2008","journal-title":"Saudi Pharm J"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089168407000604"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-8-43"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1006\/taap.1994.1127"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf8026827"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4162\/nrp.2010.4.2.114"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfi307"},{"key":"e_1_2_7_13_1","first-page":"28","article-title":"Inhibition of murine skin carcinogenesis by freeze\u2010dried grape powder and other grape\u2010derived major antioxidants","volume":"63","author":"Hanausek M","year":"2011","journal-title":"Nutr Cancer"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2009.12.012"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1878"},{"key":"e_1_2_7_16_1","unstructured":"IARC IARC monographs on the evaluation of carcinogenic risks to humans Lyon 1994 pp1\u2013560."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/09637486.2010.534438"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2013.08.003"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfl155"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2007.09.093"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8977-8-1"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.919"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/1071576031000112690"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01986538"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-012-0705-6"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(88)90265-0"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/1750-3841.12136"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.05.003"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf020302f"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(02)00078-3"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2008.05.020"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i21.2657"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.72.11.4425"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3841.2007.00481.x"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2012.05.060"}],"container-title":["Journal of Food Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1750-3841.12815","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ift.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1750-3841.12815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:12:24Z","timestamp":1762186344000},"score":1,"resource":{"primary":{"URL":"https:\/\/ift.onlinelibrary.wiley.com\/doi\/10.1111\/1750-3841.12815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,5]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/1750-3841.12815"],"URL":"https:\/\/doi.org\/10.1111\/1750-3841.12815","archive":["Portico"],"relation":{},"ISSN":["0022-1147","1750-3841"],"issn-type":[{"value":"0022-1147","type":"print"},{"value":"1750-3841","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,5]]}}}