{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:08:12Z","timestamp":1780106892212,"version":"3.54.0"},"reference-count":71,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T00:00:00Z","timestamp":1444608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Yacon (\n                    <jats:italic>Smallanthus sonchifolius<\/jats:italic>\n                    ), a native Andean plant, has been cultivated as a crop and locally used as a traditional folk medicine for the people suffering from diabetes and digestive\/renal disorders. However, the medicinal properties of this plant and its processed foods have not been completely established. This study investigates the potent antioxidative effects of herbal tea leaves from yacon in different free radical models and a ferric reducing model. A hot\u2010water extract exhibited the highest yield of total polyphenol and scavenging effect on 1,1\u2010diphenyl\u20102\u2010picryl hydrazyl (DPPH) radical among four extracts prepared with hot water, methanol, ethanol, and ethylacetate. In addition, a higher reducing power of the hot\u2010water extract was similarly demonstrated among these extracts. Varying concentrations of the hot\u2010water extract resulted in different scavenging activities in four synthetic free radical models: DPPH radical (EC\n                    <jats:sub>50<\/jats:sub>\n                    28.1 \u03bcg\/mL), 2,2\u2032\u2010azinobis(3\u2010ethylbenzothiazoline\u20106\u2010sulfonic acid) cation radical (EC\n                    <jats:sub>50<\/jats:sub>\n                    23.7 \u03bcg\/mL), galvinoxyl radical (EC\n                    <jats:sub>50<\/jats:sub>\n                    3.06 \u03bcg\/mL), and chlorpromazine cation radical (EC\n                    <jats:sub>50<\/jats:sub>\n                    475 \u03bcg\/mL). The yacon tea\u2010leaf extract further demonstrated superoxide anion (O\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) radical scavenging effects in the phenazine methosulfate\u2010NADH\u2010nitroblue tetrazolium (EC\n                    <jats:sub>50<\/jats:sub>\n                    64.5 \u03bcg\/mL) and xanthine oxidase assay systems (EC\n                    <jats:sub>50<\/jats:sub>\n                    20.7 \u03bcg\/mL). Subsequently, incubating human neutrophilic cells in the presence of the tea\u2010leaf extract could suppress the cellular O\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>\u2212<\/jats:sup>\n                    radical generation (IC\n                    <jats:sub>50<\/jats:sub>\n                    65.7 \u03bcg\/mL) in a phorbol 12\u2010myristate 13\u2010acetate\u2010activated cell model. These results support yacon tea leaves may be a good source of natural antioxidants for preventing O\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>\u2212<\/jats:sup>\n                    radical\u2010mediated disorders.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.13092","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T16:45:01Z","timestamp":1444754701000},"source":"Crossref","is-referenced-by-count":34,"title":["Antioxidant Effects of Herbal Tea Leaves from Yacon (\n                    <i>Smallanthus sonchifolius<\/i>\n                    ) on Multiple Free Radical and Reducing Power Assays, Especially on Different Superoxide Anion Radical Generation Systems"],"prefix":"10.1111","volume":"80","author":[{"given":"Shintaro","family":"Sugahara","sequence":"first","affiliation":[{"name":"School of Agriculture Tokai Univ, Kawayo, Minamiaso, Aso  Kumamoto 869\u20131404 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