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A cost\u2010effective method was developed in this study for aroma compounds extraction from grape pomace with the potential for industrial application. Based on the solvent extraction procedure, experimental factors including pretreatment, enzymatic hydrolysis time, solvent concentration and distillation time were investigated to optimize the extraction process. Volatile compounds of the pomace extract were analyzed using headspace solid\u2010phase microextraction gas\u2010chromatography mass spectrometry (HS\u2010SPME\u2010GC\u2010MS) method. Results revealed that enzymatic hydrolysis was the optimal pretreatment method. A maximum extraction efficiency was achieved under 48 hr of enzymatic hydrolysis, 70% of ethanol concentration and 20 min of distillation. A total of 65 volatile compounds were identified in the extract, including 16 alcohols, 1 alkane, 1 aldehyde, 9 esters, 3 ketones, 4 phenols, 6 terpenes, and 1 furan, of which 15 volatiles were determined as odor\u2010active compounds. This study developed a feasible extraction technique to recycle the underutilized byproducts from wine industry to produce aroma\/flavor food additives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Practical Application<\/jats:title>\n                    <jats:p>This study develops a cost\u2010effective method for aroma compounds extraction from grape pomace with the potential for industrial application as food additives.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.15533","type":"journal-article","created":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T01:23:46Z","timestamp":1605403426000},"page":"4225-4240","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Optimizing extraction method of aroma compounds from grape pomace"],"prefix":"10.1111","volume":"85","author":[{"given":"Zijian","family":"Liang","sequence":"first","affiliation":[{"name":"School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences University of Melbourne  Parkville VIC 3010 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahalya","family":"Pai","sequence":"additional","affiliation":[{"name":"School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences University of Melbourne  Parkville VIC 3010 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences University of Melbourne  Parkville VIC 3010 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqiang","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences University of Melbourne  Parkville VIC 3010 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihong","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Food Science and Nutritional Engineering China Agricultural University  Beijing 100083 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9902-3426","authenticated-orcid":false,"given":"Zhongxiang","family":"Fang","sequence":"additional","affiliation":[{"name":"School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences University of Melbourne  Parkville VIC 3010 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9794-2269","authenticated-orcid":false,"given":"Pangzhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences University of Melbourne  Parkville VIC 3010 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,14]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"465","article-title":"Coupling ultrasound with enzyme\u2010assisted extraction of essential oil from Algerian Artemisia herba\u2010alba Asso","volume":"77","author":"Agouillal F.","year":"2018","journal-title":"Journal of Scientific & Industrial Research"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf60215a074"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejlt.201600230"},{"issue":"196","key":"e_1_2_8_5_1","first-page":"2167","article-title":"A review on the extraction methods use in medicinal plants, principle, strength and limitation","volume":"4","author":"Azwanida N. 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