{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:16:58Z","timestamp":1789424218056,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T00:00:00Z","timestamp":1610928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      In this study, response surface methodology was employed to optimize the ultrasound\u2010assisted extraction (UAE) process of perilla seed meal polysaccharides (PSMP). The optimal conditions for UAE of PSMP were: liquid\u2013solid ratio of 26.00\u00a0mL\/g, ultrasonic temperature of 43.00 \u00b0C, ultrasonic time of 52.00\u00a0min, and ultrasonic power of 229.00 W, the optimal conditions lead to an yield of 6.137\u00a0\u00b1 0.062%. The structural characteristics of molecular weight, compositional monosaccharides, and glycosidic linkages were determined by size exclusion chromatography with multiangle light scattering, gas chromatography\u2010mass spectrometry, Fourier\u2010transfer infrared spectroscopy, and nuclear magnetic resonance detections. Scanning electron microscopy analysis showed that many holes were formed on the surface of PSM after UAE. The antioxidant activities of PSMP were investigated using various assays\n                      <jats:italic>in vitro<\/jats:italic>\n                      . The results suggested that PSMP is potential natural resource of antioxidants for medicine and functional foods.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Practical Application<\/jats:title>\n                    <jats:p>The selection of raw material perilla seed meal is conducive to the comprehensive utilization of edible resources. With consumer demands for newly developed foods with natural, wholesome ingredients are increasing nowadays. This study provides effective reference for in\u2010depth research on other medicine\u2010food dual\u2010use resources. Ultrasound\u2010assisted extraction (UAE) is a promising alternative method for hot water reflux extraction (HWRE) of polysaccharides for advantages of high efficiency and energy saving. In this work, the UAE process optimized by response surface methodology is more suitable for industrial application that can effectively decrease total cost of production by reducing the extraction temperature, shortening extraction time, and increasing raw material utilization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.15597","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:17:30Z","timestamp":1611015450000},"page":"306-318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Optimization of ultrasound\u2010assisted extraction of polysaccharides from perilla seed meal by response surface methodology: Characterization and\n                    <i>in vitro<\/i>\n                    antioxidant activities"],"prefix":"10.1111","volume":"86","author":[{"given":"Hongjiao","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Chemical 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