{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:03:40Z","timestamp":1791482620113,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:00:00Z","timestamp":1715644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22174080"],"award-info":[{"award-number":["22174080"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study aims to investigate the impact of four key factors, namely, temperature, water source, metal ion, and pH, on the stability of molecular chirality of dihydromyricetin (DMY) and proposed effective strategies for configuration protection. The findings reveal that temperatures exceeding 80\u00b0C could accelerate the racemization process of DMY, with a significant increase in racemization observed at 100\u00b0C. In addition, DMY exhibited heightened stability in ultrapure water as compared to various water sources, including pure water\u20101, pure water\u20102, mineral water, and running water. Notably, the presence of Fe\n                    <jats:sup>2+<\/jats:sup>\n                    displayed an inhibitory effect on the racemization of DMY, whereas Mg\n                    <jats:sup>2+<\/jats:sup>\n                    , Ca\n                    <jats:sup>2+<\/jats:sup>\n                    , and Mn\n                    <jats:sup>2+<\/jats:sup>\n                    showed a substantial promotional effect. Additionally, acidic conditions (pH\u00a0&lt;\u00a05.0) were found to be protective for maintaining the stability of DMY, whereas alkaline conditions (pH\u00a0&gt;\u00a09.0) were observed to be detrimental. Meanwhile, we first identified the presence of another pair of DMY isomers in this work.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.17105","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:25:24Z","timestamp":1715732724000},"page":"3569-3576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Study on the stability of molecular chirality and the configuration protection of dihydromyricetin in vine tea"],"prefix":"10.1111","volume":"89","author":[{"given":"Shuang","family":"Li","sequence":"first","affiliation":[{"name":"Institute of Drug Discovery and Technology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuming","family":"Sha","sequence":"additional","affiliation":[{"name":"Institute of Drug Discovery and Technology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Sun","sequence":"additional","affiliation":[{"name":"Institute of Drug Discovery and Technology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Drug Discovery and Technology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Drug Discovery and Technology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2407-949X","authenticated-orcid":false,"given":"Shaohua","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Drug Discovery and Technology Ningbo University  Ningbo China"},{"name":"Qian Xuesen Collaborative Research Center for Astrochemistry and Space Life Sciences Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2019.1588881"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0021\u20109673(99)00519\u20101"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/app122110909"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10101459"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010013\u20100022\u2010z"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2022.113625"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201078379\u2010y"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2022.107389"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021\u20109673(00)00532\u2010X"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c08535"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/bmv114"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetasy.2017.09.006"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.3178"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/chir.23495"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants11212962"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2016.08.036"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dyepig.2021.110051"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hnm.2022.200142"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/03639049409039080"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2015.06.030"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.1766"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.07.018"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.1876"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.6428"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1107\/S1600536807050416"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2014.09.090"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2017.7172"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.27154"}],"container-title":["Journal of Food Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ift.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1750-3841.17105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T17:39:32Z","timestamp":1762191572000},"score":1,"resource":{"primary":{"URL":"https:\/\/ift.onlinelibrary.wiley.com\/doi\/10.1111\/1750-3841.17105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,14]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/1750-3841.17105"],"URL":"https:\/\/doi.org\/10.1111\/1750-3841.17105","archive":["Portico"],"relation":{},"ISSN":["0022-1147","1750-3841"],"issn-type":[{"value":"0022-1147","type":"print"},{"value":"1750-3841","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,14]]},"assertion":[{"value":"2024-01-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}