{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:42:06Z","timestamp":1787013726843,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011705","name":"Korea Institute of Marine Science and Technology promotion","doi-asserted-by":"publisher","award":["20220488"],"award-info":[{"award-number":["20220488"]}],"id":[{"id":"10.13039\/501100011705","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2020M3H1A1073304"],"award-info":[{"award-number":["2020M3H1A1073304"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Capsosiphon fulvescens<\/jats:italic>\n                      (CF) is a green alga widely consumed in East Asian countries, particularly in Korea. It has a rich composition of vitamins, minerals, dietary fibers, and bioactive compounds, which contribute to its multiple therapeutic properties. Its application ranges from acting as an antioxidant and anti\u2010inflammatory agent to supporting the skin system. Despite these benefits of CF, the effects and mechanisms of action related to photoaging of the skin have not yet been elucidated. To investigate the photoprotective effects of CF against photoaging, both animal (SKH\u20101 mouse) and cell models (HaCaT cell line) were used in this study. As a result, administering the CF extract over a period of 10\u00a0weeks, which included times of Ultraviolet B (UVB) exposure, significantly reduced erythema and various UVB\u2010induced skin changes, such as wrinkle formation, and the thickening of the epidermis and dermis, as well as alterations in the length and depth of wrinkles. Furthermore, our investigation into CF extract's antiwrinkle properties revealed its efficacy in enhancing skin hydration and collagen content, counteracting the collagen depletion and moisture loss induced by UVB radiation. Also, the fact that the levels of p\u2010ERK, p\u2010p38, and p\u2010JNK proteins went down shows that the CF extract might have a controlling effect on the MAPK signaling pathways. Our findings suggest that CF holds significant potential for preventing photoaging, providing a foundation for the development of functional foods or botanical drugs targeting skin aging and related skin disorders.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Practical Application<\/jats:title>\n                    <jats:p>\n                      This research proved that\n                      <jats:italic>Capsosiphon fulvescen<\/jats:italic>\n                      , a green alga widely consumed in East Asian countries, provides photoprotective activities against UV\u2010induced skin aging. Therefore,\n                      <jats:italic>Capsosiphon fulvescen<\/jats:italic>\n                      can be utilized as functional foods or botanical drugs targeting skin aging and related skin disorders.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.17246","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T23:58:43Z","timestamp":1720742323000},"page":"5150-5163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Photoprotective activities of\n                    <i>Capsosiphon fulvescens<\/i>\n                    in UVB\u2010induced SKH\u20101 mice and human keratinocytes"],"prefix":"10.1111","volume":"89","author":[{"given":"Jiwon","family":"Seo","sequence":"first","affiliation":[{"name":"Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanhyeok","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Jo","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Han Yoon","family":"Park","sequence":"additional","affiliation":[{"name":"Bio\u2010MAX Institute Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Hyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Bio\u2010MAX Institute Seoul National University  Seoul Republic of Korea"},{"name":"Advanced Institutes of Convergence Technology Seoul National University  Suwon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6302-2432","authenticated-orcid":false,"given":"Ki Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences Seoul National University  Seoul Republic of Korea"},{"name":"Bio\u2010MAX Institute Seoul National University  Seoul Republic of Korea"},{"name":"Advanced Institutes of Convergence Technology Seoul National University  Suwon Republic of Korea"},{"name":"Institutes of Green Bio Science &amp; 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