{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:06:10Z","timestamp":1789563970972,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,11,24]],"date-time":"2024-11-24T00:00:00Z","timestamp":1732406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32101950"],"award-info":[{"award-number":["32101950"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["Z211100002121085"],"award-info":[{"award-number":["Z211100002121085"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    3\u2010Deoxyanthocyanidins (3\u2010DAS) are the unique flavonoid compounds in sorghum. The majority of research to date have concentrated on the biological activity and extraction of 3\u2010DAS from sorghum and lacked systematic purification and identification investigations. Herein, a facile method for the purification of sorghum 3\u2010DAS from the acidic methanol solution crude extract using macroporous resins (MARs) was proposed and investigated in this work. Based on the experimental data, commercial MAR AB\u20108 was selected to achieve the purification of sorghum 3\u2010DAS. The adsorption\u2010desorption experiment confirmed the optimal procedure. With this procedure, the total purity of 3\u2010DAS was 19.32%, and 3\u2010DAS content in the purified product was 8.4 times higher than that in the crude extract. UPLC\u2010QTRAP\u2010MS\/MS identification indicated that the purified 3\u2010DAS product was mainly composed of apigeninidin, luteolinidin, and their methoxy derivatives. Besides, the purified product exhibited better bioactivities than the crude extract, including the scavenging activities for DPPH, ABTS\n                    <jats:sup>+<\/jats:sup>\n                    , and hydroxyl radicals, the total antioxidant capacity, and the inhibitory effects for \u03b1\u2010amylase, \u03b1\u2010glucosidase, and lipase. This work provides a potential way for the large\u2010scale purification of bioactive sorghum 3\u2010DAS from crude extract, which is significant to deepen the applications of sorghum 3\u2010DAS in the food nutrition and pharmaceutical industries.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.17526","type":"journal-article","created":{"date-parts":[[2024,11,24]],"date-time":"2024-11-24T20:16:32Z","timestamp":1732479392000},"page":"9120-9136","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Macroporous resins combined with UPLC\u2010QTRAP\u2010MS\/MS for the purification and identification of 3\u2010deoxyanthocyanidins from\n                    <i>Sorghum bicolor<\/i>\n                    L. Moench and their bioactivities"],"prefix":"10.1111","volume":"89","author":[{"given":"Yanbei","family":"Wu","sequence":"first","affiliation":[{"name":"China\u2010Canada Joint Lab of Food Nutrition and Health Beijing Technology &amp; Business University  Beijing P. R. China"},{"name":"School of Food and Health Beijing Technology &amp; Business University  Beijing P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueling","family":"Yu","sequence":"additional","affiliation":[{"name":"China\u2010Canada Joint Lab of Food Nutrition and Health Beijing Technology &amp; Business University  Beijing P. R. China"},{"name":"School of Food and Health Beijing Technology &amp; Business University  Beijing P. R. 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