{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:28:50Z","timestamp":1789388930536,"version":"build-2803163510"},"reference-count":70,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Marine collagen is gaining more attraction than terrestrial collagen because it is free of zoonotic disease and religious constrain. In this study, we aimed to investigate and compare the physicochemical properties and functional characteristics of acid\u2010soluble collagen (ASC\u2010MF) and pepsin\u2010soluble collagen (PSC\u2010MF) extracted from scales of\n                    <jats:italic>Megalonibea fusca<\/jats:italic>\n                    . ASC\u2010MF and PSC\u2010MF were evaluated in terms of yield, collagen type, amino acid composition, thermal stability, microstructure, cytotoxicity, and other physicochemical parameters. ASC\u2010MF and PSC\u2010MF depicted 1.72\u00a0\u00b1\u00a00.2% and 11.72\u00a0\u00b1\u00a00.3% of dry weight yields, respectively, and were identified as type I collagen with an intact triple\u2010helical structure by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS\u2010PAGE), spectroscopic analysis, and electron microscopy. Additionally, compared with many temperate and tropical species, ASC\u2010MF and PSC\u2010MF showed higher thermal stability, with the maximum transition temperature (\n                    <jats:italic>T<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    ) of 53.50\u00b0C (ASC\u2010MF) and 43.16\u00b0C (PSC\u2010MF). CCK\u20108 assay showed that ASC\u2010MF and PSC\u2010MF have no cytotoxicity in vitro. The determination of blood clotting index values showed that both ASC\u2010MF and PSC\u2010MF had good hemostatic ability. In summary, these findings show that PSC\u2010MF isolated from the scales of\n                    <jats:italic>M. fusca<\/jats:italic>\n                    may be a feasible alternative to terrestrial collagen sources in food and biomedical applications.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.17644","type":"journal-article","created":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T12:19:32Z","timestamp":1735561172000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Extraction, characterization, and hemostatic effect of collagen from the scales of\n                    <i>Megalonibea fusca<\/i>"],"prefix":"10.1111","volume":"90","author":[{"given":"Guangfeng","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cell Biology, College of Life Science and Technology Jinan University  Guangzhou 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Technology Jinan University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoxi","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, College of Life Science and Technology Jinan University  Guangzhou China"},{"name":"Key Laboratory of Innovative Technology Research on Natural Products and Cosmetics Raw Materials  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, College of Life Science and Technology Jinan University  Guangzhou China"},{"name":"Guangdong Pharmaceutical University  Guangzhou China"},{"name":"Key Laboratory of Innovative Technology Research on Natural Products and Cosmetics Raw Materials  Guangzhou China"},{"name":"Guangdong Provincial Biotechnology Drug &amp; Engineering Technology Research Center  Guangzhou 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