{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T17:37:19Z","timestamp":1772300239862,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Brown seaweed oligosaccharides (BSO) have demonstrated potential as nutraceuticals with cholesterol\u2010lowering, anti\u2010obesity, and anti\u2010constipation properties. In this study, we initially examined how BSO impact body weight, blood lipid levels, and adipose tissue in a rat model of obesity induced by a high\u2010fat diet. Our findings revealed that BSO administration significantly attenuated body weight gain, ameliorated dyslipidemia, and reduced visceral adiposity. Additionally, we evaluated the prophylactic efficacy of BSO in a loperamide hydrochloride\u2010induced constipation mouse model by assessing defecation parameters and gastrointestinal motility. Our results indicated that BSO intervention significantly increased fecal pallet output and fecal water content, as well as improved intestinal transit. In conclusion, this study lays the foundation for a deeper understanding of how BSO may influence obesity and constipation, offering novel insights into its potential safe and efficacious clinical applications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.17647","type":"journal-article","created":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T12:05:36Z","timestamp":1735560336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of brown seaweed oligosaccharides on obesity and constipation managements"],"prefix":"10.1111","volume":"90","author":[{"given":"Jingyu","family":"Gao","sequence":"first","affiliation":[{"name":"College of Food Science and Nutritional Engineering China Agricultural University  Beijing China"},{"name":"National Engineering Research Center for Fruit and Vegetable Processing  Beijing China"},{"name":"Key Laboratory of Fruit and Vegetable Processing Ministry 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