{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:06:23Z","timestamp":1787587583510,"version":"build-2736575974"},"reference-count":114,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Driven by the increasing interest in the incorporation of naturally derived ingredients in functional foods, researchers have placed greater emphasis on the process of identifying bioactive constituents from medicinal plants, as they can provide health benefits and nutritional potential. This study offers a phytochemical profiling and bioactivities investigation conducted for the first time for an Algerian wild\n                    <jats:italic>Foeniculum vulgare<\/jats:italic>\n                    subsp.\n                    <jats:italic>capillaceum<\/jats:italic>\n                    , focusing on its potential for functional food applications. Extracts from the aerial portions of the plant were prepared using a sequence of solvents, starting from\n                    <jats:italic>n<\/jats:italic>\n                    \u2010hexane, followed by acetone, methanol, and finally deionized water to efficiently separate compounds based on their solubility characteristics. Subsequently, these extracts were subjected to a detection, characterization, and precise quantification of the diverse phenolic constituents present in the samples with LC\u2010MS\/MS. A total of 17 phenolic metabolites were characterized, with rutin and chlorogenic acid emerging as the major constituents. Among the extracts, the methanolic fraction demonstrated the greatest concentration of overall identified phenolic compounds (11.874\u00a0mg\/g), accompanied by notable antioxidant capacity reflected in its effective neutralization of free radicals, recording IC\u2085\u2080 measurements of 28.69\u00a0\u00b5g\/mL for DPPH radical and 24.72\u00a0\u00b5g\/mL for ABTS cations. Interestingly, the hexanic extract demonstrated the strongest\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010amylase inhibition (50.06% at 400\u00a0\u00b5g\/mL), suggesting antidiabetic potential, while the acetonic extract displayed notable antibacterial activity, particularly against\n                    <jats:italic>Micrococcus luteus<\/jats:italic>\n                    (MIC = 1.56\u00a0mg\/mL). These findings highlight\n                    <jats:italic>F. vulgare<\/jats:italic>\n                    subsp.\n                    <jats:italic>capillaceum<\/jats:italic>\n                    as a rich reservoir of compounds with biological activities positions it as a promising addition to functional foods designed to improve nutritional value and safety.\n                  <\/jats:p>","DOI":"10.1111\/1750-3841.70436","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T10:58:36Z","timestamp":1753095516000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chemical Profiling via LC\u2010ESI\u2010MS\/MS and Functional Bioactivities of\n                    <i>Foeniculum vulgare<\/i>\n                    subsp.\n                    <i>Capillaceum<\/i>\n                    : Insights Into Antioxidant, Antidiabetic, and Antibacterial Potentials for Food Applications"],"prefix":"10.1111","volume":"90","author":[{"given":"Maroua","family":"Hadji","sequence":"first","affiliation":[{"name":"Biodiversity and Biotechnological Techniques for Plant Resources Valorization Laboratory (BTB_VRV), Department of Natural and Life Sciences, Faculty of Sciences University of M'sila, University Pole  M'sila Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamdi","family":"Bendif","sequence":"additional","affiliation":[{"name":"Biology Department, College of Science Imam Mohammad Ibn Saud Islamic University (IMSIU)  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toka","family":"Hadji","sequence":"additional","affiliation":[{"name":"Laboratory of the Development and Valorization of Plant Genetic Resources, Department of Biology and Plant Ecology University of Mentouri Brothers Constantine 1  Constantine Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadidja","family":"Dehimi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Biochemistry, Faculty of Sciences University of M'sila, University Pole  M'sila Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahar","family":"Smaili","sequence":"additional","affiliation":[{"name":"Biodiversity and Biotechnological Techniques for Plant Resources Valorization Laboratory (BTB_VRV), Department of Natural and Life Sciences, Faculty of Sciences University of M'sila, University Pole  M'sila Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kebaili Fethi","family":"Farouk","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiological Engineering and Application, Department of Biochemistry and Molecular and Cellular Biology Faculty of Nature and Life Sciences University of Mentouri Brothers Constantine 1  Constantine Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilyas","family":"Yildiz","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences and Arts, Department of Molecular Biology and Genetics Tokat Gaziosmanpa\u015fa University  Tokat T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A. M.","family":"Ali","sequence":"additional","affiliation":[{"name":"Biology Department, College of Science Imam Mohammad Ibn Saud Islamic University (IMSIU)  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"Erenler","sequence":"additional","affiliation":[{"name":"Application and Research Center (ALUM), Foundation of the Faculty of Health Sciences, Nutrition and Dietetics Department I\u011fd\u0131r University  I\u011fd\u0131r T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal","family":"Lahouaou","sequence":"additional","affiliation":[{"name":"Laboratory of Plant Biotechnology and Ethnobotany, Department of Physical and Chemical Biology University of Bejaia  Bejaia Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fehmi","family":"Boufahja","sequence":"additional","affiliation":[{"name":"Biology Department, College of Science Imam Mohammad Ibn Saud Islamic University (IMSIU)  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8535-0533","authenticated-orcid":false,"given":"Stefania","family":"Garzoli","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Technologies of Drug Sapienza University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2020.09.004"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fshw.2019.03.004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116961"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcab.2023.102639"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12071959"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0378\u20108741(80)81015\u20104"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2021.131231"},{"issue":"5","key":"e_1_2_9_9_1","first-page":"81","article-title":"The Chemical Constituents and Pharmacological Effects of Foeniculum vulgare\u2014A Review","volume":"8","author":"Al\u2010Snafi A. 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