{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:56:13Z","timestamp":1790567773051,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>The previous study found that a structured lipid rich in \u03b1\u2010linolenic acid (ALA\u2010SL) is prone to oxidative rancidity due to its high degree of unsaturation. To improve its oxidative stability and targeted slow\u2010release behavior during gastrointestinal digestion, ALA\u2010SL microcapsules (ALA\u2010SLMs) were prepared by freeze\u2010drying in this study. Under optimal conditions, ALA\u2010SLMs exhibited an excellent embedding efficiency of 98.00% \u00b1 0.46%, with an approximately spherical structure, particle size concentrated between 1 and 10\u00a0\u00b5m, and good uniformity verified by a span value of 1.92. After 60 days of storage at 4\u00b0C, 25\u00b0C, 40\u00b0C, and 60\u00b0C, the peroxide value (PV) of unencapsulated ALA\u2010SL was 1.02\u2010, 1.06\u2010, 1.01\u2010, and 1.11\u2010fold higher than that of ALA\u2010SLMs, respectively. In vitro simulated digestion demonstrated its characteristic intestinal sustained\u2010release behavior, which provides preliminary in vitro evidence that may favor enhanced intestinal absorption of \u03b1\u2010linolenic acid (ALA); however, further cellular or animal trials are required to quantitatively validate its actual in vivo bioavailability improvement. Molecular docking predicted that \u03b2\u2010cyclodextrin (\u03b2\u2010CD) only forms weak shallow non\u2010covalent complexes with ALA via cavity\u2010mouth hydrogen bonds, which offers limited molecular\u2010level protection for unsaturated fatty acids.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.71419","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T03:47:29Z","timestamp":1788148049000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Soy Protein Isolate\u2013\u03b2\u2010Cyclodextrin Microencapsulation Boosts Stability and Intestinal Delivery of \u03b1\u2010Linolenic Acid\u2010Rich Structured Lipids: Oxidation, Digestion, and Molecular Docking 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