{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:55:30Z","timestamp":1790567730360,"version":"4.1.0"},"reference-count":183,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Xylooligosaccharides (XOS) are highly promising functional prebiotics with excellent stability and intestinal regulatory activity, whose physiological efficacy is strictly dependent on their degree of polymerization (DP), with low\u2010DP XOS (DP 2\u20133, mainly xylobiose and xylotriose) being the core active components. Recent advances in lignocellulosic biorefinery and enzymatic engineering have greatly expanded XOS feedstock sources and improved production efficiency, while the controllable preparation and efficient application of high\u2010purity low\u2010DP XOS remain the core bottleneck restricting the high\u2010quality development of the XOS industry. This review systematically summarizes the latest research progress of lignocellulose\u2010derived XOS, covering feedstock screening and evaluation, preparation technology comparison, DP\u2010dependent functional mechanisms, and multi\u2010scenario application advances. It highlights the unique advantages of mild organic acid pretreatment combined with specific enzymatic hydrolysis in low\u2010DP XOS production, and the broad application prospects of low\u2010DP XOS in precision nutrition and biomedicine, providing a comprehensive theoretical reference for subsequent research. Emerging promising approaches include continuous\u2010flow reactors with real\u2010time DP monitoring and high\u2010specificity GH11 xylanase engineering, while future research will focus on targeted synthesis of specific DP XOS, in\u2010depth dissection of molecular action mechanisms, and development of customized functional products.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.71482","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T04:00:29Z","timestamp":1789358429000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Targeted Preparation of Low\u2010Degree Polymerization Xylooligosaccharides From Lignocellulosic Biomass: Advances, Structure\u2013Activity Relationships, and Applications"],"prefix":"10.1111","volume":"91","author":[{"given":"Xuan","family":"Ge","sequence":"first","affiliation":[{"name":"State Key Laboratory for Development and 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