{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:55:48Z","timestamp":1790567748858,"version":"4.1.0"},"reference-count":75,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food Science"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      Green tea kombucha is an antioxidant\u2010rich beverage with promising health benefits. However, evidence regarding its effects in physically active individuals remains limited. This study investigated the acute and chronic effects of green tea kombucha, with or without grape skin extract, on immune and oxidative stress markers in beginner runners. This 12\u2010week randomized clinical trial included 90 healthy adults (18\u201345 years) allocated to three groups: control (CT\u2010G), green tea kombucha (GT\u2010G), and green tea kombucha with grape skin extract (GTG\u2010G). Participants performed supervised running training three times weekly following a polarized periodization model. Kombucha intake was not associated with significant changes in the primary outcome, ferric reducing antioxidant power (FRAP), nor in acute immune or oxidative responses to exercise (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a00.05). However, during the chronic period, the GT\u2010G showed increased neutrophils (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.026) and reduced lymphocytes (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.023) compared to the other groups. Fasting catalase (CAT) activity differed between groups GT\u2010G and CT\u2010G (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.037), despite no significant group x time interaction (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.157). A group \u00d7 time interaction was detected for post\u2010exercise malondialdehyde concentrations (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.033), with no significant interaction in the post hoc test. Sensitivity analyses including all randomized participants confirmed the primary observations; however, false discovery rate (FDR) adjustments indicated these findings are exploratory. No additional effects were detected in GTG\u2010G. In conclusion, 12 weeks of green tea kombucha intake was associated with nominally significant changes in immune and oxidative markers during chronic running training, and further studies are needed to clarify these findings.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1750-3841.71505","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:41:30Z","timestamp":1790419290000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute and Chronic Effects of Green Tea Kombucha With and Without Grape Skin Extract on Immune and Oxidative Stress Markers in Beginner Runners: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0618-5275","authenticated-orcid":false,"given":"Dandara Baia","family":"Bonif\u00e1cio","sequence":"first","affiliation":[{"name":"Department of Nutrition and Health Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayanne Santos","family":"de Paulo","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Health Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Henrique Viana","family":"Mendes","sequence":"additional","affiliation":[{"name":"Department of Physical Education Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udielle Vermelho","family":"Lacerda","sequence":"additional","affiliation":[{"name":"Department of Food and Technology Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Rezende","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Department of Food and Technology Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helton de S\u00e1","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Physical Education Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7300-8773","authenticated-orcid":false,"given":"Frederico Augusto Ribeiro","family":"de Barros","sequence":"additional","affiliation":[{"name":"Department of Food and Technology Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefina","family":"Bressan","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Health Universidade Federal de Vi\u00e7osa  Vi\u00e7osa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11072078"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742\u20105573\u20108\u20101"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.5114\/biolsport.2023.116005"},{"issue":"123","key":"e_1_2_10_5_1","first-page":"556","article-title":"Reliability and Applicability of an Incremental Track Test With a Pacer Bicycle: A New and Alternative to Treadmill Protocols","volume":"19","author":"Amorim R. 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