{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T11:01:06Z","timestamp":1792321266545,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T00:00:00Z","timestamp":1361145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy and safety of endoscopic papillary large\u2010balloon dilation (<jats:styled-content style=\"fixed-case\">EPLBD<\/jats:styled-content>) combined with limited endoscopic sphincterotomy (<jats:styled-content style=\"fixed-case\">EST<\/jats:styled-content>) for the removal of large biliary duct stones (\u226510\u2009mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data of patients who underwent an attempted removal of large bile duct stones by limited <jats:styled-content style=\"fixed-case\">EST<\/jats:styled-content> followed by <jats:styled-content style=\"fixed-case\">EPLBD<\/jats:styled-content> (\u226512\u2009mm in diameter) from <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pril 2006 to <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ctober 2011 in our center were reviewed. Clinical characteristics, endoscopic methods and outcomes of the patients were collected and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 169 patients with a mean age of 69.3 years (range 19\u201397 years) underwent 171 procedures. Median stone size and balloon diameter was 15\u2009mm and 13\u2009mm, respectively. Complete stone removal in a single session was achieved in 163 procedures (95.3%) with mechanical lithotripsy (<jats:styled-content style=\"fixed-case\">ML<\/jats:styled-content>) used in 66 (38.6%). Patients with a larger stone size required more frequent use of ML with a comparable success rate (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). There were no significant differences between patients with and without periampullary diverticula in stone clearance (97.3% <jats:italic>vs<\/jats:italic> 93.8%), <jats:styled-content style=\"fixed-case\">ML<\/jats:styled-content> requirement (36.5% <jats:italic>vs<\/jats:italic> 40.2%) and complications (2.7% <jats:italic>vs<\/jats:italic> 6.2%) (all <jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). Seven patients had eight procedure\u2010related complications including moderate or mild bleeding (<jats:italic>n<\/jats:italic>\u2009=\u20094), minor perforation (<jats:italic>n<\/jats:italic>\u2009=\u20091), mild pancreatitis (<jats:italic>n<\/jats:italic>\u2009=\u20092) and cholangitis (<jats:italic>n<\/jats:italic>\u2009=\u20091).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">EPLBD<\/jats:styled-content> following limited <jats:styled-content style=\"fixed-case\">EST<\/jats:styled-content> is an effective and safe approach for the removal of large biliary duct stones, especially for those refractory cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12013","type":"journal-article","created":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T07:31:06Z","timestamp":1353483066000},"page":"125-131","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Endoscopic papillary large\u2010balloon dilation following limited sphincterotomy for the removal of refractory bile duct stones: Experience of 169 cases in a single <scp>C<\/scp>hinese center"],"prefix":"10.1111","volume":"14","author":[{"given":"Xiao Ming","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Endoscopy Eastern Hepatobiliary Surgery Hospital Second Military Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Eastern Hepatobiliary Surgery Hospital Second Military Medical University  Shanghai 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