{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:07:49Z","timestamp":1761919669041},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,15]],"date-time":"2013-04-15T00:00:00Z","timestamp":1365984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify risk factors, clinical features and complications in patients with ischemic colitis (<jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients diagnosed with biopsy proven <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content> within a 2\u2010year period were identified; clinical data were retrospectively collected and subsequently analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 72 <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content> patients with a mean age of 68\u2009years were included in this study. Among them, 18 (25.0%) were younger than 65 years with a female predominance. One\u2010third of the patients was found to be without vascular risk factors, and 8 patients met the criteria for irritable bowel syndrome. No history of oral contraceptives or hormonal replacement therapy use could be found among the women diagnosed with <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content>. Over a mean duration of follow\u2010up of 9.5 months (range 0\u201365\u2009months), the rate of recurrent disease was 16.7%, while only 2 (2.8%) patients developed extra intestinal vascular sequelae. Statistical analysis identified a history of atrial fibrillation and the use of furosemide to be the only significant predictors of a poor outcome, while coronary artery disease and chronic renal failure predicted recurrence and low platelet count predicted stricture formation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although most patients with <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content> are elderly and have conventional vascular risk factors, it should also be considered in young patients without vascular risk factors, especially in women, who may have an atypical distribution of the disease. Severe complications and extraintestinal vascular sequelae are rare, however, residual gastrointestinal complaints and recurrent disease are relatively common and there are no reliable predictors of the outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12045","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T18:49:44Z","timestamp":1361299784000},"page":"238-243","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Retrospective analysis of disease association and outcome in histologically confirmed ischemic colitis"],"prefix":"10.1111","volume":"14","author":[{"given":"Mahmoud","family":"Mosli","sequence":"first","affiliation":[{"name":"Departments of Medicine and Pathology London Health Sciences Centre University of Western Ontario  London Ontario Canada"},{"name":"Department of Medicine King Abdulaziz University Hospital King Abdulaziz University  Jeddah Kingdom of Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Parfitt","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Pathology London Health Sciences Centre University of Western Ontario  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamie","family":"Gregor","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Pathology London Health Sciences Centre University of Western Ontario  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2002\/374682"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2003.11.022"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.02.016"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0104-4230(12)70147-1"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastrohep.2010.10.005"},{"key":"e_1_2_5_7_1","first-page":"667","article-title":"Ischemic colitis induced by cocaine. Clinical case","volume":"130","author":"Boza C","year":"2002","journal-title":"Rev Med Chil"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-200009000-00015"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1001228"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018839415743"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199701000-00011"},{"key":"e_1_2_5_12_1","first-page":"1558","article-title":"Ischemic colitis related to cocaine abuse","volume":"89","author":"Brown DN","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_13_1","first-page":"1011","article-title":"Ischemic colitis after cocaine abuse","volume":"16","author":"Pauwels A","year":"1992","journal-title":"Gastroenterol Clin Biol"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00459.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.25"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.25.4.620.61032"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.01903.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.00328.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.21436.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2007.01015.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-255X(01)80067-6"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.4166\/kjg.2012.60.1.19"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-003-0033-6"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i36.4564"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050319"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199903000-00014"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02554499"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.09.018"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199504000-00007"},{"key":"e_1_2_5_30_1","first-page":"305","article-title":"Digestive complications of oral contraceptives: a case of extensive digestive necrosis in a young woman","volume":"38","author":"Carpentier E","year":"1984","journal-title":"Ann Chir"},{"key":"e_1_2_5_31_1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/17843286.1993.11718284","article-title":"Ischemic colitis in a patient with Crohn's disease taking an oral contraceptive and an ergotamine alkaloid","volume":"48","author":"Rutgeerts L","year":"1993","journal-title":"Acta Clin Belg"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.SMJ.0000066655.54770.88"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6918(03)00021-0"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(00)70183-1"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2007.03250.x"}],"container-title":["Journal of Digestive Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1751-2980.12045","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1751-2980.12045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T17:53:06Z","timestamp":1697392386000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1751-2980.12045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,15]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/1751-2980.12045"],"URL":"https:\/\/doi.org\/10.1111\/1751-2980.12045","archive":["Portico"],"relation":{},"ISSN":["1751-2972","1751-2980"],"issn-type":[{"value":"1751-2972","type":"print"},{"value":"1751-2980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,15]]},"assertion":[{"value":"2013-04-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}