{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:41:33Z","timestamp":1697445693909},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T00:00:00Z","timestamp":1369699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The study aimed to compare the clinical characteristics of abdominopelvic (AP) abscess in patients with and without newly diagnosed Crohn's disease (CD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We investigated 91 consecutive patients with <jats:styled-content style=\"fixed-case\">AP<\/jats:styled-content> abscess (14 newly diagnosed with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>) from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2001 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2010. The clinical, radiological, microbiological and pathological features and patients' outcomes were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with newly diagnosed <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> were younger (42.5 <jats:italic>vs<\/jats:italic> 57.9 years, <jats:italic>P<\/jats:italic>\u2009=\u20090.004), more associated with fever (50.0% <jats:italic>vs<\/jats:italic> 13.0%, <jats:italic>P<\/jats:italic>\u2009=\u20090.004) and weight loss (21.4% <jats:italic>vs<\/jats:italic> 3.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.045), and normoglycemic (5.2\u2009mmol\/L <jats:italic>vs<\/jats:italic> 6.7\u2009mmol\/L, <jats:italic>P<\/jats:italic>\u2009=\u20090.001). Their abscesses, located predominantly at the paracolic gutter region (<jats:italic>P<\/jats:italic>\u2009=\u20090.002) were associated with fistulae (<jats:italic>P<\/jats:italic>\u2009=\u20090.001) and caused by transmural bowel wall inflammation. More patients in the <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> group required temporarily parenteral nutritional support (<jats:italic>P<\/jats:italic>\u2009=\u20090.000) and had a longer hospital stay (<jats:italic>P<\/jats:italic>\u2009=\u20090.045) and a higher local recurrent rate (<jats:italic>P<\/jats:italic>\u2009=\u20090.000).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AP<\/jats:styled-content> abscesses associated with newly diagnosed <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> display distinct clinical behavior with a high risk of local recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12058","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T07:06:46Z","timestamp":1364022406000},"page":"373-381","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous abdominopelvic abscess as an initial manifestation of <scp>C<\/scp>rohn's disease: A retrospective cohort review"],"prefix":"10.1111","volume":"14","author":[{"given":"Siu\u2010Tong","family":"Law","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine and Geriatrics Tuen Mun Hospital  Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kin Kong","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine and Geriatrics Tuen Mun Hospital  Hong Kong SAR 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