{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T06:22:30Z","timestamp":1749882150822},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,10,2]],"date-time":"2013-10-02T00:00:00Z","timestamp":1380672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the diagnostic yield of repeat upper gastrointestinal endoscopy for patients with functional dyspepsia (<jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of the database including consecutive patients who underwent esophagogastroduodenoscopy at least twice for dyspeptic symptoms at a tertiary endoscopy center from 1996 to 2011 was performed. The patients' age, gender, symptoms and endoscopic and pathological findings were collected and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 2 350 patients with <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> with a median age of 50 years, including 1\u2009020 men and 1\u2009330 women, were enrolled. Abdominal pain or discomfort was the main indication for the first endoscopy, and 12.6% of the patients presented with alarm features. At the second endoscopy, non\u2010atrophic and atrophic gastritis were the most common endoscopic findings and only 12 and 10 patients were found to have peptic ulcers or gastric polyps, respectively. No malignancy was detected at either the first or the repeat endoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Significant pathologies within one year after a normal esophagogastroduodenoscopy are very rare for patients with <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content>. Therefore, a repeat endoscopy within one year after the first endoscopy is not recommended for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12090","type":"journal-article","created":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T11:14:37Z","timestamp":1374232477000},"page":"574-578","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic yield of repeat upper gastrointestinal endoscopy for patients with functional dyspepsia"],"prefix":"10.1111","volume":"14","author":[{"given":"Jie Fang","family":"Guo","sequence":"first","affiliation":[{"name":"Digestive Endoscopy Center Department of Gastroenterology Changhai Hospital Second Military Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Bai","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center Department of Gastroenterology Changhai Hospital Second Military Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao Shen","family":"Li","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center Department of Gastroenterology Changhai Hospital Second Military Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40052.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31815591f7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.192401"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02553-8"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7344.999"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.13.1606"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.147728"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.736"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06759.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.45.2008.ii37"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i20.2520"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.01015.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.58"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.043570"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.meg.0000108366.19243.3a"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.09.020"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2011.00548.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2009.05108.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.22124"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-825853"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.4161\/jig.1.2.15048"}],"container-title":["Journal of Digestive Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1751-2980.12090","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1751-2980.12090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T09:18:24Z","timestamp":1696238304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1751-2980.12090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,2]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/1751-2980.12090"],"URL":"https:\/\/doi.org\/10.1111\/1751-2980.12090","archive":["Portico"],"relation":{},"ISSN":["1751-2972","1751-2980"],"issn-type":[{"value":"1751-2972","type":"print"},{"value":"1751-2980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,2]]},"assertion":[{"value":"2013-10-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}