{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T05:40:51Z","timestamp":1696398051598},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T00:00:00Z","timestamp":1390521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the type of cardiac mucosa and its relationship with age and gender of the participants and to determine the coincidence of endoscopic and pathological diagnosis of carditis as well as its etiology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data of 70 patients with carditis (the carditis group) and 30 individuals with endoscopically normal\u2010appearing cardiac mucosa (the control group), including their baseline characteristics and histopathological findings, were reviewed. Their <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>elicobacter pylori<\/jats:italic> (<jats:italic>H. pylori<\/jats:italic>) status was also reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three main types of cardiac mucosa: mucous, oxyntic and mixed types, were found in 45.0%, 40.0% and 15.0% of all the participants, respectively. The distribution of these types was related to the age of the participants but not to their gender. Moderate to severe mucosal inflammation was detected in 60.0% (18\/30) of the control group. The etiologies of cardiac inflammation were <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u2009pylori<\/jats:italic> infection and gastroesophageal reflux disease (<jats:styled-content style=\"fixed-case\">GERD)<\/jats:styled-content>. For antral <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u2009pylori<\/jats:italic>\u2010negative participants, cardiac mucosal inflammation was correlated with esophageal mucosal inflammation (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), while for those with antral <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u2009pylori<\/jats:italic> infection it was associated with antral mucosal inflammation (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The distribution of different cardiac mucosal types was related to the participants' age. Normal\u2010appearing cardiac mucosa under endoscopy might present with histopathologically moderate to severe cardiac inflammation. The etiologies of cardiac inflammation were <jats:italic><jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>.\u2009pylori<\/jats:italic> infection and <jats:styled-content style=\"fixed-case\">GERD<\/jats:styled-content>. Different causes of carditis may result in the different histological performance of the cardia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12108","type":"journal-article","created":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T03:01:06Z","timestamp":1382583666000},"page":"71-77","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Etiology and morphology of carditis: Experiences from a single center in <scp>C<\/scp>hina"],"prefix":"10.1111","volume":"15","author":[{"given":"Qi","family":"Miao","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Divison of Gastrointestinal Pathology, Shanghai Institute of Digestive Disease  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao Zhou","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Divison of Gastrointestinal Pathology, Shanghai Institute of Digestive Disease  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gan Hui","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Divison of Gastrointestinal Pathology, Shanghai Institute of Digestive Disease  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Divison of Gastrointestinal Pathology, Shanghai Institute of Digestive Disease  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.01930.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200304000-00010"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.6.791"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.04053.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.5858\/2003-127-0451-HOGJIF","article-title":"of gastroesophageal junction in fetal and pediatric autopsy","volume":"127","author":"Park YS","year":"2003","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2005.02088.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200307000-00008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200301000-00009"},{"key":"e_1_2_6_10_1","first-page":"144","article-title":"Features of chronic inflammation at the gastric cardia and the relationship with Helicobacter pylori infection and oesophagitis","volume":"66","author":"Ayhan S","year":"2003","journal-title":"Acta Gastroenterol Belg"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200003000-00002"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02000.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199610000-00001"},{"issue":"1","key":"e_1_2_6_14_1","first-page":"87","article-title":"Histological criteria for the diagnosis of reflux esophagitis","volume":"27","author":"Frierson HF","year":"1992","journal-title":"Pathol Annu"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.16.1.36"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200003000-00009"},{"key":"e_1_2_6_17_1","first-page":"13","article-title":"Histological features of gastric cardia in adults: an autopsy study","volume":"20","author":"Stojsic ZM","year":"2011","journal-title":"J Gastrointestin Liver Dis"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.3748\/wjg.v11.i29.4490","article-title":"On the origin of cardiac mucosa: a histological and immunohistochemical study of cytokeratin expression patterns in the developing esophagogastric junction region and stomach","volume":"11","author":"De Hertogh G","year":"2005","journal-title":"World J Gastroenterol"},{"key":"e_1_2_6_19_1","first-page":"32","volume-title":"World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Digestive System","author":"Spechlex SJ","year":"2000"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.08.023"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0705-0"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05462.x"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200102000-00013"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31802c9dd5"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200307000-00011"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.05324.x"}],"container-title":["Journal of Digestive Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1751-2980.12108","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1751-2980.12108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T16:50:03Z","timestamp":1696351803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1751-2980.12108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,24]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/1751-2980.12108"],"URL":"https:\/\/doi.org\/10.1111\/1751-2980.12108","archive":["Portico"],"relation":{},"ISSN":["1751-2972","1751-2980"],"issn-type":[{"value":"1751-2972","type":"print"},{"value":"1751-2980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,24]]},"assertion":[{"value":"2014-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}