{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:44:47Z","timestamp":1783943087845,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,9,28]],"date-time":"2015-09-28T00:00:00Z","timestamp":1443398400000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy, safety and feasibility of microwave ablation (<jats:styled-content style=\"fixed-case\">MWA<\/jats:styled-content>) for large (5\u201310\u2009cm in diameter) hepatic hemangioma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In all, 46 patients with 47 large hepatic hemangiomas were treated with ultrasound\u2010guided percutaneous <jats:styled-content style=\"fixed-case\">MWA<\/jats:styled-content>. The effect of <jats:styled-content style=\"fixed-case\">MWA<\/jats:styled-content> for all patients was evaluated by enhanced magnetic resonance imaging or computed tomography within two months after ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 27 male and 19 female patients were enrolled, with an average age of 46\u2009\u00b1\u200911 years. The average size of hemangiomas was 6.3\u2009\u00b1\u20091.4\u2009cm (range 5.0\u20139.6\u2009cm). The initial complete ablation rate was 91.5% (43\/47) and the volume of ablated lesions was significantly reduced. The rate of complete necrosis was not associated with the tumor size or location (<jats:italic>P<\/jats:italic>\u2009<jats:italic>=<\/jats:italic>\u20090.899 and 0.758, respectively). The total complete ablation rate was 95.7% (45\/47). Major complications included acute renal dysfunction, hyperbilirubinemia and pleural effusion. No procedure\u2010related death occurred. The average hospitalization stay was 5.7\u2009\u00b1\u20092.5 days (range 3\u201317 days). During a follow\u2010up period of 18.2 months (range 4\u201340 months), one patient developed local tumor progression at the radiofrequency ablation site. Three patients had new hemangiomas in other sites of the liver. At the end of the study all patients were alive and no severe complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Image\u2010guided <jats:styled-content style=\"fixed-case\">MWA<\/jats:styled-content> is an effective and safe treatment for large hepatic hemangiomas, and can potentially be regarded as the first\u2010line therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12169","type":"journal-article","created":{"date-parts":[[2014,6,19]],"date-time":"2014-06-19T15:32:54Z","timestamp":1403191974000},"page":"525-530","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Efficacy, safety and feasibility of ultrasound\u2010guided percutaneous microwave ablation for large hepatic hemangioma"],"prefix":"10.1111","volume":"16","author":[{"given":"Xiao Yin","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Interventional Oncology Renji Hospital School 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