{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:56:32Z","timestamp":1790517392233,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T00:00:00Z","timestamp":1413417600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2014,10]]},"abstract":"Objective<\/jats:title>Most previous studies exploring the overlap of functional gastrointestinal disorders (FGID) focus on the overlap between functional dyspepsia (FD<\/jats:styled-content>) and irritable bowel syndrome (IBS<\/jats:styled-content>). In this study, we aimed to explore the spectra, symptom profiles and overlap of all FGID<\/jats:styled-content> using the validated C<\/jats:styled-content>hinese version of the R<\/jats:styled-content>ome III<\/jats:styled-content> questionnaire.<\/jats:p><\/jats:sec>Methods<\/jats:title>Consecutive newly diagnosed FGID<\/jats:styled-content> patients who were admitted to the Outpatient Gastroenterology Clinic from 10 M<\/jats:styled-content>ay to 10 S<\/jats:styled-content>eptember 2012 were recruited in the study. All the patients complained of gastrointestinal (GI) symptoms for at least 3 months with a symptom onset of at least 6 months before diagnosis after excluded organic diseases. Patients who met the inclusion criteria were asked to complete the scoring algorithm for the R<\/jats:styled-content>ome III<\/jats:styled-content> integrated questionnaire.<\/jats:p><\/jats:sec>Results<\/jats:title>Among 350 eligible patients, 302 (86.3%) returned completed questionnaires. A total of six major domains including 17 disorders were diagnosed. The four most prevalent FGID<\/jats:styled-content> were FD<\/jats:styled-content> (54.6%), IBS<\/jats:styled-content> (40.7%), unspecified functional bowel disorder (13.9%) and functional constipation (12.6%). The three most prevalent symptoms in FGID<\/jats:styled-content> were abdominal pain (66.2%), loose stool (58.3%) and abdominal bloating\/distension (56.3%). Of the 302 patients, 152 (50.3%) had one to five overlapping FGID<\/jats:styled-content>. Only functional bloating had no overlap. Six patients had five overlapping FGID<\/jats:styled-content> simultaneously. In all, 63 patients had overlapping FD<\/jats:styled-content> and IBS<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>This study provided the detailed spectra and symptom profiles for all FGID<\/jats:styled-content>. Overlapping FGID<\/jats:styled-content> are common in C<\/jats:styled-content>hina.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12178","type":"journal-article","created":{"date-parts":[[2014,8,8]],"date-time":"2014-08-08T10:20:48Z","timestamp":1407493248000},"page":"538-544","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The spectra, symptom profiles and overlap of R<\/scp>ome III<\/scp> functional gastrointestinal disorders in a tertiary center in S<\/scp>outh C<\/scp>hina"],"prefix":"10.1111","volume":"15","author":[{"given":"Li Shou","family":"Xiong","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Rong","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Hu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou Guangdong Province 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