{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,25]],"date-time":"2024-08-25T00:43:01Z","timestamp":1724546581790},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T00:00:00Z","timestamp":1419897600000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2014,12]]},"abstract":"Objective<\/jats:title>Early cholecystectomy is currently the gold standard treatment for acute cholecystitis (AC<\/jats:styled-content>). However, the acceptability and safety of this strategy remain in dispute. The aim of this study was to clarify the role of percutaneous transhepatic gallbladder aspiration (PTGBA<\/jats:styled-content>) in the early management of AC<\/jats:styled-content> in a single center.<\/jats:p><\/jats:sec>Methods<\/jats:title>A total of 147 consecutive patients who were treated with PTGBA<\/jats:styled-content> for AC<\/jats:styled-content> from 2008 to 2012 were included in the study. The therapeutic outcomes and adverse events were evaluated.<\/jats:p><\/jats:sec>Results<\/jats:title>A single PTGBA<\/jats:styled-content> was adequate for 96 (65.3%) patients with AC<\/jats:styled-content>. Of the remaining 51 patients, 43 (29.3%) showed an improvement after repeated PTGBA<\/jats:styled-content> and\/or percutaneous transhepatic gallbladder drainage (PTGBD<\/jats:styled-content>), while semi\u2010emergency cholecystectomy was needed in eight patients. Although five patients experienced adverse events (intra\u2010abdominal hemorrhage in two, bile leakage in two and gallbladder hemorrhage in one), no patient died of treatment\u2010related complications. Subsequently, 87 (59.2%) patients underwent cholecystectomy after PTGBA<\/jats:styled-content> (a single PTGBA<\/jats:styled-content> in 48 and repeated PTGBA<\/jats:styled-content> and\/or PTGBD<\/jats:styled-content> in 39 patients). No significant differences were observed in the conversion rate from laparoscopic surgery to open cholecystectomy, operative time or intraoperative hemorrhage volume between the two groups.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The present study demonstrated the safety and acceptability of treatment with PTGBA<\/jats:styled-content> for AC<\/jats:styled-content> at our center. This elective treatment strategy may be a useful alternative option in the treatment of AC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12198","type":"journal-article","created":{"date-parts":[[2014,9,19]],"date-time":"2014-09-19T08:28:00Z","timestamp":1411115280000},"page":"669-675","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Role of percutaneous transhepatic gallbladder aspiration in the early management of acute cholecystitis"],"prefix":"10.1111","volume":"15","author":[{"given":"Shohei","family":"Komatsu","sequence":"first","affiliation":[{"name":"Department of Surgery Yodogawa Christian Hospital Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Department of Hepato\u2010Biliary\u2010Pancreatic Surgery Osaka City General Hospital Osaka 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