{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:39:46Z","timestamp":1790033986016,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T00:00:00Z","timestamp":1419897600000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the association of dietary behavior with refractory functional dyspepsia (<jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content>) and its subtypes in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of patients admitted to the <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>utpatient <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epartment of <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>astroenterology of four hospitals in Mainland China for upper gastrointestinal (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>) symptoms from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>une to <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2012 were reviewed and their characteristics were collected. Functional dyspepsia (<jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content>) was diagnosed based on the <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>ome <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> criteria. <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content> was defined as <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> with continuous symptoms for at least 6 months that was unresponsive to at least two kinds of medications. Another 100 healthy volunteers were included as controls. The participants' dietary behaviors were investigated using a questionnaire survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 1341 <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> patients were enrolled in the study, including 327 <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content> and 1014 non\u2010<jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">NRFD<\/jats:styled-content>). Unhealthy dietary behaviors were more prevalent in both <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">NRFD<\/jats:styled-content> than in the healthy controls. Skipping meals, eating extra meals and a preference to sweet food and gas\u2010producing food were more common in the <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content> patients. Compared with <jats:styled-content style=\"fixed-case\">NRFD<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content>\u2010epigastric pain syndrome (<jats:styled-content style=\"fixed-case\">EPS<\/jats:styled-content>) patients preferred spicy food, whereas those with postprandial distress syndrome (<jats:styled-content style=\"fixed-case\">PDS<\/jats:styled-content>) preferred sweet food and gas\u2010producing food, and those with both <jats:styled-content style=\"fixed-case\">EPS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PDS<\/jats:styled-content> were found to skip meals and take extra meals more often. Logistic regression analysis showed that skipping meals, eating extra meals and a preference to sweet food and gas\u2010producing food were risk factors for <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Unhealthy dietary behaviors, especially skipping meals, eating extra meals and a preference to sweet food and gas\u2010producing food, were correlated with <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content> and its subtypes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12199","type":"journal-article","created":{"date-parts":[[2014,10,6]],"date-time":"2014-10-06T09:43:54Z","timestamp":1412588634000},"page":"654-659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Unhealthy dietary behavior in refractory functional dyspepsia: A multicenter prospective investigation in <scp>C<\/scp>hina"],"prefix":"10.1111","volume":"15","author":[{"given":"Shu Man","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Guangzhou First People's Hospital Guangzhou Medical University  Guangzhou China"},{"name":"Department of Gastroenterology Guangzhou Nansha Central Hospital  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Gai","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Guangzhou First People's Hospital Guangzhou Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Guangzhou First People's Hospital Guangzhou Medical University  Guangzhou China"},{"name":"Department of Gastroenterology Guangzhou Nansha Central Hospital  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Guangdong No. 2 Provincial People's Hospital  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng Bing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Meizhou Municipal People's Hospital  Meizhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Guangzhou First People's Hospital Guangzhou Medical University  Guangzhou China"},{"name":"Department of Gastroenterology Guangzhou Nansha Central Hospital  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Guangzhou First People's Hospital Guangzhou Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06648.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2012.18.2.150"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06353.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.16493"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.059"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2010.4.2.173"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2011.01.012"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00846582"},{"key":"e_1_2_6_10_1","first-page":"101","article-title":"Behavioral cardiology \u2013 has its time finally arrived?","volume":"70","author":"Pickering T","year":"2003","journal-title":"Mt Sinai J Med"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.02.093"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.11.001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2008.01260.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i32.4379"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01872.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1024\/1661-8157\/a000095"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068383"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpgasthep0685"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2007.03277.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0698-8"},{"key":"e_1_2_6_21_1","first-page":"97","article-title":"Food and nutrient intakes and eating patterns in functional and organic dyspepsia","volume":"48","author":"Mullan A","year":"1994","journal-title":"Eur J Clin Nutr"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06632.x"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.00288.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365529850171819"}],"container-title":["Journal of Digestive Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1751-2980.12199","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1751-2980.12199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:57:09Z","timestamp":1696334229000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1751-2980.12199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/1751-2980.12199"],"URL":"https:\/\/doi.org\/10.1111\/1751-2980.12199","archive":["Portico"],"relation":{},"ISSN":["1751-2972","1751-2980"],"issn-type":[{"value":"1751-2972","type":"print"},{"value":"1751-2980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"2014-12-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}