{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:29:24Z","timestamp":1792628964059,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T00:00:00Z","timestamp":1479859200000},"content-version":"vor","delay-in-days":83,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Acquiring adequate tissue for immunohistochemical (IHC) analysis is important in the differential diagnosis of subepithelial tumors (SETs). In this study, we aimed to compare the diagnostic yield based on IHC analysis between endoscopic ultrasound\u2010guided fine needle aspiration (EUS\u2010FNA) and EUS\u2010guided fine needle biopsy (EUS\u2010FNB) after on\u2010site cytological evaluation for cellularity in gastric SETs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In 22 patients with gastric SETs, EUS\u2010guided tissue sampling was performed on the same SET in a randomized sequence, with EUS\u2010FNA followed by EUS\u2010FNB, or\n                      <jats:italic>vice versa<\/jats:italic>\n                      . After on\u2010site cytological evaluation for cellularity, the cytological and histological examinations were performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a significant difference in the median number of needle passes to obtain adequate cellularity in the on\u2010site cytological evaluation (2.0 for EUS\u2010FNA\n                      <jats:italic>vs<\/jats:italic>\n                      1.0 for EUS\u2010FNB,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.008). The proportion of adequate cellularity on the first needle pass was significantly higher in the EUS\u2010FNB than in the EUS\u2010FNA group (68.2%\n                      <jats:italic>vs<\/jats:italic>\n                      31.8%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.034). However, diagnosis based on IHC examination was established in 15 (68.2%) and 18 (81.8%) cases by EUS\u2010FNA and EUS\u2010FNB, respectively (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.488).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EUS\u2010FNB decreases the number of needle passes to obtain adequate cellularity and yields a higher proportion of adequate cellularity during the first needle pass compared with EUS\u2010FNA in gastric SETs. However, there was no significant difference in diagnostic yield with IHC stain between the two procedures after on\u2010site cytological evaluation for adequate cellularity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1751-2980.12381","type":"journal-article","created":{"date-parts":[[2016,7,16]],"date-time":"2016-07-16T05:42:35Z","timestamp":1468647755000},"page":"582-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["EUS\u2010guided FNA and FNB after on\u2010site cytological evaluation in gastric subepithelial tumors"],"prefix":"10.1111","volume":"17","author":[{"given":"Jae Pil","family":"Han","sequence":"first","affiliation":[{"name":"Digestive Disease Center and Research Institute, Department of Internal Medicine and Pathology Soonchunhyang University College of Medicine  Bucheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Digestive Disease Center and Research Institute, Department of Internal Medicine and Pathology Soonchunhyang University College of Medicine  Bucheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su Jin","family":"Hong","sequence":"additional","affiliation":[{"name":"Digestive Disease Center and Research Institute, Department of Internal Medicine and Pathology Soonchunhyang University College of Medicine  Bucheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Digestive Disease Center and Research Institute, Department of Internal Medicine and Pathology Soonchunhyang University College of Medicine  Bucheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung Min","family":"Noh","sequence":"additional","affiliation":[{"name":"Digestive Disease Center and Research Institute, 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