{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T06:07:50Z","timestamp":1769234870117,"version":"3.49.0"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T00:00:00Z","timestamp":1555804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to evaluate the safety and efficiency of radiofrequency ablation (RFA) in Chinese patients with gastroesophageal reflux disease (GERD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center, prospective study including 27 Chinese patients with GERD. The outcomes in all patients were evaluated before and at 3, 6, and 12\u2009months after RFA, including their GERD health\u2010related quality of life (GERD\u2010HRQL) score, esophageal acid exposure, DeMeester score, lower esophageal sphincter (LES) resting pressure, and patient's satisfaction with symptom control. Furthermore, rabeprazole sodium (RS) administration, reflux esophagitis (RE), and intraoperative and postoperative complications were also evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>RFA treatment significantly reduced the GERD\u2010HRQL score, the percentage of time that esophageal pH\u2009&lt;\u20094, and the DeMeester score, and significantly increased the LES resting pressure in GERD patients. A need for RS administration was reduced and RE symptoms were relieved. Satisfaction rate of 92.6% and 96.3% was reported by these patients at 6 and 12\u2009months post\u2010treatment, respectively. Mild bleeding (&lt;20 mL) occurred in one patient during RFA, and no serious intraoperative and postoperative complications were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>RFA is safe and effective in the treatment of GERD in Chinese patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.12722","type":"journal-article","created":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T08:54:36Z","timestamp":1552640076000},"page":"229-234","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Radiofrequency ablation is safe and effective in the treatment of Chinese patients with gastroesophageal reflux disease: A single\u2010center prospective study"],"prefix":"10.1111","volume":"20","author":[{"given":"Pei Pei","family":"Liu","sequence":"first","affiliation":[{"name":"Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital Second Military Medical University (Naval Medical University)  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2564-8105","authenticated-orcid":false,"given":"Qian Qian","family":"Meng","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital Second Military Medical University (Naval Medical University)  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Lin","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital Second Military Medical University (Naval Medical University)  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Neurology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Qian","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital Second Military Medical University (Naval Medical University)  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao Shen","family":"Li","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital Second Military Medical University (Naval Medical University)  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8474-0601","authenticated-orcid":false,"given":"Luo Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital Second Military Medical University (Naval Medical University)  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-67202014000300013"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv512"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304269"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.444"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-10-94"},{"issue":"3","key":"e_1_2_6_7_1","first-page":"249","article-title":"Proton pump inhibitor\u2010refractory gastroesophageal reflux disease: current diagnosis and management","volume":"63","author":"Frazzoni L","year":"2017","journal-title":"Minerva Gastroenterol Dietol."},{"issue":"4","key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"222","DOI":"10.4103\/sjg.SJG_573_16","article-title":"Effect of long\u2010term proton pump inhibitor administration on gastric mucosal atrophy: A meta\u2010analysis","volume":"23","author":"Li Z","year":"2017","journal-title":"Saudi J Gastroenterol."},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","unstructured":"ArathyT BincyV SindhujaBV IreneK NayanaM JemiV.Consequences and complications of long term use of proton pump inhibitors. 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