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As the natural history and variety of clinical presentations of this disease unfolds, extrapulmonary symptoms of COVID\u201019 have emerged, especially in the digestive system. While the respiratory mode of transmission is well known and is probably the principal mode of transmission of this disease, a possibility of the fecal\u2010oral route of transmission has also emerged in various case series and clinical scenarios. In this review article, we summarize four different aspects in published studies to date: (a) gastrointestinal manifestations of COVID\u201019; (b) microbiological and virological investigations; (c) the role of fecal\u2010oral transmission; and (d) prevention and control of SARS\u2010CoV\u20102 infection in the digestive endoscopy room. A timely understanding of the relationship between the disease and the digestive system and implementing effective preventive measures are of great importance for a favorable outcome of the disease and can help climnicians to mitigate further transmission by taking appropriate measures.<\/jats:p>","DOI":"10.1111\/1751-2980.12862","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T09:41:01Z","timestamp":1586338861000},"page":"199-204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Digestive system involvement of novel coronavirus infection: Prevention and control infection from a gastroenterology perspective"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0852-7005","authenticated-orcid":false,"given":"Lian Yong","family":"Li","sequence":"first","affiliation":[{"name":"Department of Gastroenterology PLA Strategic Support Force Characteristic 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