{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:04:45Z","timestamp":1784297085471,"version":"3.55.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T00:00:00Z","timestamp":1660953600000},"content-version":"vor","delay-in-days":50,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800462"],"award-info":[{"award-number":["81800462"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020LZL003"],"award-info":[{"award-number":["ZR2020LZL003"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the management of <jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H. pylori<\/jats:italic>) infection by gastroenterologists from secondary and tertiary hospitals in Shandong Province, China, where there is a high prevalence of <jats:italic>H. pylori<\/jats:italic> infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A questionnaire\u2010based, stratified sampling survey was conducted from June 1 to August 30, 2021. The ratio of secondary to tertiary hospitals was set at 2:1. An electronic questionnaire was sent to the gastroenterologists via the WeChat platform.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 89.09% (1053\/1182) gastroenterologists were included. Overall, 34.19% and 60.59% of gastroenterologists recommended screening for and treating <jats:italic>H. pylori<\/jats:italic> infection in patients without any competing factors. The most preferred testing method in secondary and tertiary hospitals was the <jats:sup>13<\/jats:sup>C\u2010urea breath test (53.92% and 80.48%), but the reexamination rate of results close to the cut\u2010off value was low (55.10% and 59.48%). Gastroenterologists preferred bismuth\u2010containing quadruple therapy (secondary and tertiary hospitals: 96.67% and 98.53%), but the antibiotic combination prescribed for patients with penicillin allergy was suboptimal in secondary hospitals. The overall post\u2010treatment follow\u2010up rate was 64.58%, and gastroenterologists in secondary hospitals were more proactive than those in tertiary hospitals (69.41% vs 60.04%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001). Less than 80% of gastroenterologists emphasized the importance of post\u2010treatment reexamination to their patients. Only a minority of gastroenterologists in secondary and tertiary hospitals (30.79% and 34.36%) achieved acceptable eradication rates (exceeding 80%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Deficiencies exist in gastroenterologists from secondary and tertiary hospitals, and the <jats:italic>H. pylori<\/jats:italic> eradication rate is relatively low. Training programs for gastroenterologists are warranted to strengthen their comprehension of guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.13119","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T07:28:20Z","timestamp":1658820500000},"page":"365-375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical practice of <i>Helicobacter pylori<\/i> infection management by gastroenterologists in secondary and tertiary hospitals: A stratified sampling cross\u2010sectional survey"],"prefix":"10.1111","volume":"23","author":[{"given":"Wen Lin","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue Yue","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"},{"name":"Laboratory of Translational Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Shen","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Juan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Ming","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing Zhou","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao Tong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong Xue","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5637-7796","authenticated-orcid":false,"given":"Rui","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"},{"name":"Laboratory of Translational Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province China"},{"name":"Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor Qilu Hospital of Shandong University  Jinan Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9556-8771","authenticated-orcid":false,"given":"Xiu Li","family":"Zuo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Qilu Hospital, Cheeloo College of Medicine Shandong University  Jinan Shandong Province 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