{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:00:06Z","timestamp":1773270006844,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T00:00:00Z","timestamp":1683331200000},"content-version":"vor","delay-in-days":94,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970557"],"award-info":[{"award-number":["81970557"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82003152"],"award-info":[{"award-number":["82003152"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Prolonged preparation\u2010to\u2010colonoscopy (PC) interval and insufficient purgative intake (PI) are two important indicators for quality of bowel preparation for colonoscopy. We aimed to investigate patient\u2010related factors associated with increased PC interval or insufficient PI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The post\u2010hoc regression analyses were performed using the data from two prospective studies (NCT04434625 and NCT04101097). Patients receiving reinforced instructions for bowel preparation were recruited. The co\u2010primary outcomes included prolonged PC interval or insufficient PI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Altogether 1806 patients from five endoscopic centers underwent bowel preparation from September 2019 to March 2021. The cut\u2010off values were 6\u2009h for PC interval and 80% for PI. In all, 116 (6.4%) and 73 (4.0%) presented an extended PC interval and insufficient PI, respectively. Multivariate logistic regression analysis showed that a low education level was significantly associated with PC interval \u22656\u2009h. Female sex, body mass index (BMI), and coronary artery disease (CAD) were found to be significantly correlated with insufficient PI\u2009in univariate analysis, while multivariate analysis demonstrated BMI\u2009&lt;20 kg\/m<jats:sup>2<\/jats:sup> (odds ratio [OR] 4.14, 95% confidence interval [CI] 1.92\u20138.94, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and 20\u201325 kg\/m<jats:sup>2<\/jats:sup> (OR 2.23, 95% CI 1.33\u20133.73, <jats:italic>P<\/jats:italic> = 0.002) and CAD (OR 3.23, 95% CI 1.22\u20138.53, <jats:italic>P<\/jats:italic>\u2009=\u20090.018) were identified as independent risk factors for PI &lt;80%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In spite of reinforced education, a number of patients did not follow the instructions for bowel preparation. The factors for a prolonged PC interval did not overlap with those for insufficient PI. Individualized interference may be considered in different subpopulations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.13170","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T01:39:25Z","timestamp":1681090765000},"page":"133-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Patient\u2010related factors related to prolonged preparation\u2010to\u2010colonoscopy interval and insufficient purgative intake before colonoscopy: A post\u2010hoc observational study"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8844-5263","authenticated-orcid":false,"given":"Xiao Yu","family":"Kang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an Shaanxi Province 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 Xi'an Shaanxi Province China"},{"name":"Department of Infectious Diseases Xijing Hospital, Fourth Military Medical University  Xi'an Shaanxi Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an Shaanxi Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an Shaanxi Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gui","family":"Ren","sequence":"additional","affiliation":[{"name":"State Key Laboratory of 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