{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T22:24:18Z","timestamp":1775082258655,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970479"],"award-info":[{"award-number":["81970479"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170577"],"award-info":[{"award-number":["82170577"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515010187"],"award-info":[{"award-number":["2023A1515010187"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Anti\u2010reflux mucosectomy (ARMS) is an emerging and promising endoscopic treatment for gastroesophageal reflux disease (GERD). In the current study we aimed to evaluate the safety and efficacy of ARMS in treating Chinese GERD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center prospective cohort study. ARMS was performed in GERD patients by an experienced endoscopist. The patients were required to undergo symptom assessment as well as endoscopic examination, high\u2010resolution manometry (HRM), and impedance\u2010pH monitoring before and after ARMS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve patients were enrolled. Follow\u2010up was completed by all patients at 3 and 6\u2009months, 11 patients at 1\u2009year, and 8 patients at 2\u2009years after ARMS, respectively. Symptom improvement was achieved in 66.7%, 75.0%, 72.7%, and 50.0% of the patients at 3\u2009months, 6\u2009months, 1\u2009year, and 2\u2009years after ARMS, respectively. Postoperative dysphagia was reported by 25.0%, 25.0%, 27.3%, and 25.0% of patients at 3\u2009months, 6\u2009months, 1\u2009year, and 2\u2009years after surgery, none of whom required additional invasive treatment. All patients with preoperative esophagitis healed after ARMS. For impedance\u2010pH monitoring parameters, number of acidic reflux episodes and the proportion of patients with acid exposure time (AET) &gt;4.0% decreased significantly after ARMS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ARMS was safe and effective in Chinese GERD patients. The efficacy of ARMS was not short\u2010term and remained evident throughout the 2\u2010year follow\u2010up. Further multicenter studies with larger sample sizes are needed to verify our findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.13238","type":"journal-article","created":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T05:45:36Z","timestamp":1698903936000},"page":"611-618","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Two\u2010year outcomes of anti\u2010reflux mucosectomy in treating gastroesophageal reflux disease: A Chinese prospective cohort study"],"prefix":"10.1111","volume":"24","author":[{"given":"Jun Nan","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou Guangdong Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6448-0395","authenticated-orcid":false,"given":"Song 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