{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:28:46Z","timestamp":1747182526323,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":39,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The Japan <jats:styled-content style=\"fixed-case\">NBI<\/jats:styled-content> Expert Team (<jats:styled-content style=\"fixed-case\">JNET<\/jats:styled-content>) classification has good diagnostic potential for colorectal diseases. We aimed to explore the diagnostic value of the JNET classification type 2B (JNET2B) criteria for colorectal laterally spreading tumors (LSTs) based on magnifying endoscopy with blue laser imaging (ME\u2010BLI) examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2017 and June 2023, 218 patients who were diagnosed as having JNET2B\u2010type LSTs using ME\u2010BLI were included retrospectively. Endoscopic images were reinterpreted to categorize the LSTs as JNET2B\u2010low (n\u2009=\u2009178) and JNET2B\u2010high (n\u2009=\u200953) LSTs. The JNET2B\u2010low and JNET2B\u2010high LSTs were compared based on their histopathological and morphological classifications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 178 JNET2B\u2010low LSTs, 86 (48.3%) were histopathologically classified as low\u2010grade intraepithelial neoplasia, 54 (30.3%) as high\u2010grade intraepithelial neoplasia (HGIN), 37 (20.8%) as intramucosal carcinoma (IMC), and one (0.6%) as superficial invasive submucosal carcinoma (SMC1). Among the 53 JNET2B\u2010high LSTs, five (9.4%) were classified as HGIN, 28 (52.9%) as IMC, 15 (28.3%) as SMC1, and 5 (9.4%) as deep invasive submucosal carcinoma. There were significant differences in this histopathological classification between the two groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). However, there was no significant difference between JNET2B\u2010low and JNET2B\u2010high LSTs based on their morphological classification (granular\u00a0vs nongranular) or size (&lt;20\u2009mm vs\u2009\u226520\u2009mm). Besides, the \u03ba value for JNET2B subtyping was 0.698 (95% confidence interval\u20090.592\u20130.804) between the two endoscopists who reassessed the endoscopic images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The JNET2B subtyping of LSTs has a diagnostic potential in the preoperative setting, and may be valuable for treatment decision\u2010making.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.13296","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T06:24:13Z","timestamp":1720679053000},"page":"361-367","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the extended <scp>Japan NBI<\/scp> expert team classification of subtype <scp>2B<\/scp> in laterally spreading colorectal tumors based on blue laser imaging"],"prefix":"10.1111","volume":"25","author":[{"given":"Lin Fu","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support Force of PLA Fuzhou Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long Ping","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support Force of PLA Fuzhou Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin Xin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support Force of PLA Fuzhou Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support Force of PLA Fuzhou Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuan Shen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support Force of PLA Fuzhou Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi Rui","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support Force of PLA Fuzhou Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da Zhou","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fuzong Clinical Medical College of Fujian Medical University  Fuzhou Fujian Province China"},{"name":"Department of Gastroenterology, The 900th Hospital of Joint Logistic Support 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