{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T03:33:48Z","timestamp":1763436828781,"version":"3.32.0"},"reference-count":39,"publisher":"Wiley","issue":"9-10","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":59,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>In this study we aimed to comprehensively evaluate the clinical features and treatment outcomes of Chinese patients with autoimmune pancreatitis (AIP) through a single\u2010center real\u2010world study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients diagnosed with AIP in Changhai Hospital, Naval Medical University from January 2014 to December 2021 were included. Baseline characteristics, laboratory test results, cross\u2010sectional imaging and endoscopic ultrasound (EUS) findings, and long\u2010term follow\u2010up data were obtained. The differences in these characteristics between type 1 and type 2 AIP patients were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among all 320 patients, 271 (84.7%) and 49 (15.3%) had type 1 and type 2 AIP, respectively. The most common initial symptom was abdominal discomfort (58.1%), followed by obstructive jaundice (32.5%). Extrapancreatic organ involvement was identified in 126 (39.4%) patients, with the biliary system being the most commonly involved (36.6%). Elevated serum IgG4 level was rare in type 2 AIP patients. The diagnostic accuracy of computed tomography (CT), magnetic resonance imaging (MRI), and EUS for definitive and probable AIP were 78.0%, 68.7%, and 80.5%, respectively. EUS\u2010guided tissue acquisition with immunohistochemical staining helped establish a final diagnosis in 39.7% of patients. During the follow\u2010up period of 60\u2009months, 18.6% of patients experienced relapse. The 1\u2010, 3\u2010, and 5\u2010year relapse rates were higher in type 1 AIP patients, with an accumulated rate of 8.0%, 12.6%, and 15.1%, when compared with those with type 2 AIP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Type 2 AIP is not uncommon in Chinese population. The diagnostic accuracy of CT and EUS for AIP might be superior to that of MRI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1751-2980.13316","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T04:07:38Z","timestamp":1730347658000},"page":"615-623","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical characteristics, imaging diagnostic accuracy, and prognosis of autoimmune pancreatitis: A real\u2010world study in China"],"prefix":"10.1111","volume":"25","author":[{"given":"Yue","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Ling","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Navy Medical University  Shanghai 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