{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:58:41Z","timestamp":1792425521900,"version":"4.5.0"},"reference-count":91,"publisher":"Wiley","issue":"11-12","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"vor","delay-in-days":65,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Endoscopic submucosal dissection (ESD) is the preferred treatment for early gastric cancer and gastric adenomas. However, ESD\u2010induced artificial ulcers leads to\u00a0pain, bleeding, and delayed healing. In recent years, advances have been made for the treatment of post\u2010ESD ulcers. Currently available treatment options for post\u2010ESD ulcers include proton pump inhibitors and potassium\u2010competitive acid blockers, mucosal protective agents such as rebamimide, and novel biomaterials such as fibrin glue and hydrogel\u2010based products. In addition, advanced imaging technologies such as Doppler probe ultrasound and infrared imaging systems have been adopted to assist in the detection of invisible vessels. These novel approaches have shown promising efficacies in promoting ulcer healing and reducing post\u2010procedure adverse events. Here we review the factors that might influence ulcer healing after ESD and the recent advances in the management of ESD\u2010induced iatrogenic gastric ulcers. Further investigation is warranted regarding their long\u2010term safety, cost\u2010effectiveness, and individualized treatment strategies.<\/jats:p>","DOI":"10.1111\/1751-2980.70023","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:51:46Z","timestamp":1767678706000},"page":"460-469","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Advances in the Treatment of Gastric Artificial Ulcers Following Endoscopic Submucosal Dissection (\n                    <scp>ESD<\/scp>\n                    )"],"prefix":"10.1111","volume":"26","author":[{"given":"Yue Yao","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Zhejiang Chinese Medical University  Hangzhou Zhejiang Province 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