{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:03:49Z","timestamp":1777903429349,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":57,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372921 (T.C.)"],"award-info":[{"award-number":["82372921 (T.C.)"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82473094 (M.D.X.)"],"award-info":[{"award-number":["82473094 (M.D.X.)"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["2024ZDXK0001 (M.D.X.)"],"award-info":[{"award-number":["2024ZDXK0001 (M.D.X.)"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["22120240372 (T.C.)"],"award-info":[{"award-number":["22120240372 (T.C.)"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Appendiceal orifice lesions are occasionally detected during colonoscopy in patients with recurrent appendicitis. Conventional surgery with partial cecal resection may cause unnecessary trauma. Transcolonic endoscopic appendectomy (TEA) has been proposed as a minimally invasive alternative. We aimed to evaluate the feasibility, safety, and efficacy of transcolonic endoscopic appendectomy and to compare through\u2010the\u2010scope twin clips (TTS\u2010TC)\u00a0combined with metal clips versus metal clips alone for defect closure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty patients with recurrent appendicitis and no prior abdominal surgery who underwent transcolonic endoscopic appendectomy between December 2020 and December 2024 were included. Clinical and pathological variables, procedural parameters, and follow\u2010up outcomes were analyzed. TTS\u2010TC plus metal clips and metal clips alone for defect\u00a0closure were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All procedures were technically and clinically successful. Postoperative time to resume diet and length of hospital stay were 4.05 and 6.40 days, respectively. TTS\u2010TC combined with metal clips reduced suture time (18\u2009min [interquartile range {IQR} 15.5\u201320 min] vs. 25\u2009min [IQR 20\u201330 min]), procedure time (85\u2009min [IQR 72.5\u201392 min] vs. 115\u2009min [IQR 110\u2013124 min]), and number of clips used (7 [IQR 6.5\u20138] vs. 8 [IQR 7\u20139]) compared with metal clips alone. No adverse events were reported. Colonoscopy performed at 3 months post\u2010procedure showed no residual lesions or recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TEA is a feasible, safe, and effective approach for recurrent appendicitis with orifice lesions. It provides a minimally invasive dual\u2010benefit strategy and can be facilitated by a novel closure method to streamline the procedure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1751-2980.70040","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:15:02Z","timestamp":1772968502000},"page":"31-39","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcolonic Endoscopic Appendectomy: A Single\u2010Step \u201cTwo\u2010In\u2010One\u201d Approach for Recurrent Appendicitis With Appendiceal Orifice Lesions"],"prefix":"10.1111","volume":"27","author":[{"given":"Hao","family":"Wu","sequence":"first","affiliation":[{"name":"Endoscopy Center, Shanghai East Hospital Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhu Kai","family":"Chen","sequence":"additional","affiliation":[{"name":"Endoscopy Center, Shanghai East Hospital Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai Ping","family":"Xu","sequence":"additional","affiliation":[{"name":"Endoscopy Center, Shanghai East Hospital Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Chu","sequence":"additional","affiliation":[{"name":"Endoscopy Center, Shanghai East Hospital Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Shanghai East Hospital Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing Jing","family":"Lian","sequence":"additional","affiliation":[{"name":"Endoscopy Center, Shanghai East Hospital Tongji University  Shanghai 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