{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:37:26Z","timestamp":1791110246009,"version":"4.1.0"},"reference-count":61,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T00:00:00Z","timestamp":1357776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Biotechnology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Biological control of plant diseases has gained acceptance in recent years.\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                      acillus subtilis\n                    <\/jats:italic>\n                    \u2005\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639 is an antagonistic strain specifically selected for the efficient control of the cucurbit powdery mildew fungus\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                      odosphaera fusca\n                    <\/jats:italic>\n                    , which is a major threat to cucurbits worldwide. The antagonistic activity relies on the production of the antifungal compounds iturin and fengycin. In a previous study, we found that\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639 was able to induce systemic resistance (\n                    <jats:styled-content style=\"fixed-case\">ISR<\/jats:styled-content>\n                    ) in melon and provide additional protection against powdery mildew. In the present work, we further investigated in detail this second mechanism of biocontrol by\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639. First, we examined the signalling pathways elicited by\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639 in melon plants, as well as the defence mechanisms activated in response to\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                      .\u2009fusca\n                    <\/jats:italic>\n                    . Second, we analysed the role of the lipopeptides produced by\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639 as potential determinants for\n                    <jats:styled-content style=\"fixed-case\">ISR<\/jats:styled-content>\n                    activation. Our results demonstrated that\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639 confers protection against cucurbit powdery mildew by activation of jasmonate\u2010 and salicylic acid\u2010dependent defence responses, which include the production of reactive oxygen species and cell wall reinforcement. We also showed that surfactin lipopeptide is a major determinant for stimulation of the immune response. These results reinforce the biotechnological potential of\n                    <jats:styled-content style=\"fixed-case\">UMAF<\/jats:styled-content>\n                    6639 as a biological control agent.\n                  <\/jats:p>","DOI":"10.1111\/1751-7915.12028","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T06:27:32Z","timestamp":1357799252000},"page":"264-274","source":"Crossref","is-referenced-by-count":202,"title":["The antagonistic strain\n                    <i>\n                      <scp>B<\/scp>\n                      acillus subtilis\n                    <\/i>\n                    \u2005\n                    <scp>UMAF<\/scp>\n                    6639 also confers protection to melon plants against cucurbit powdery mildew by activation of jasmonate\u2010 and salicylic acid\u2010dependent defence responses"],"prefix":"10.1111","volume":"6","author":[{"given":"Laura","family":"Garc\u00eda\u2010Guti\u00e9rrez","sequence":"first","affiliation":[{"name":"Instituto de Hortofruticultura Subtropical y Mediterr\u00e1nea \u2018La Mayora\u2019 (IHSM\u2010UMA\u2010CSIC) Departamento de Microbiolog\u00eda Universidad de M\u00e1laga  Bulevar Louis Pasteur 31 (Campus Universitario de Teatinos) 29071 M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houda","family":"Zeriouh","sequence":"additional","affiliation":[{"name":"Instituto de Hortofruticultura Subtropical y Mediterr\u00e1nea \u2018La Mayora\u2019 (IHSM\u2010UMA\u2010CSIC) Departamento de Microbiolog\u00eda Universidad de M\u00e1laga  Bulevar Louis Pasteur 31 (Campus Universitario de Teatinos) 29071 M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Romero","sequence":"additional","affiliation":[{"name":"Instituto de Hortofruticultura Subtropical y Mediterr\u00e1nea \u2018La Mayora\u2019 (IHSM\u2010UMA\u2010CSIC) Departamento de Microbiolog\u00eda Universidad de M\u00e1laga  Bulevar Louis Pasteur 31 (Campus Universitario de Teatinos) 29071 M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Cubero","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n y Tecnolog\u00eda Agraria y Alimentaria (INIA)  Ctra de La Coru\u00f1a km 7.5 28040 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"de Vicente","sequence":"additional","affiliation":[{"name":"Instituto de Hortofruticultura Subtropical y Mediterr\u00e1nea \u2018La Mayora\u2019 (IHSM\u2010UMA\u2010CSIC) Departamento de Microbiolog\u00eda Universidad de M\u00e1laga  Bulevar Louis Pasteur 31 (Campus Universitario de Teatinos) 29071 M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"P\u00e9rez\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Instituto de Hortofruticultura Subtropical y Mediterr\u00e1nea \u2018La Mayora\u2019 (IHSM\u2010UMA\u2010CSIC) Departamento de Microbiolog\u00eda Universidad de M\u00e1laga  Bulevar Louis Pasteur 31 (Campus Universitario de Teatinos) 29071 M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Plant Pathology","author":"Agrios G.N.","year":"2005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1006\/pmpp.1993.1033"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocontrol.2003.11.005"},{"key":"e_1_2_6_5_1","first-page":"256","volume-title":"The Powdery Mildews. 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