{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:03:56Z","timestamp":1791608636624,"version":"4.3.4"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T00:00:00Z","timestamp":1482105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006456","name":"Bundesministerium f\u00fcr Wirtschaftliche Zusammenarbeit und Entwicklung","doi-asserted-by":"publisher","award":["102 701 24"],"award-info":[{"award-number":["102 701 24"]}],"id":[{"id":"10.13039\/501100006456","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Biotechnology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    In order to replace particularly biohazardous nematocides, there is a strong drive to finding natural product\u2010based alternatives with the aim of containing nematode pests in agriculture. The metabolites produced by the fungal endophyte\n                    <jats:italic>Fusarium oxysporum<\/jats:italic>\n                    162 when cultivated on rice media were isolated and their structures elucidated. Eleven compounds were obtained, of which six were isolated from a\n                    <jats:italic>Fusarium<\/jats:italic>\n                    spp. for the first time. The three most potent nematode\u2010antagonistic compounds, 4\u2010hydroxybenzoic acid, indole\u20103\u2010acetic acid (\n                    <jats:styled-content style=\"fixed-case\">IAA<\/jats:styled-content>\n                    ) and gibepyrone D had\n                    <jats:styled-content style=\"fixed-case\">LC<\/jats:styled-content>\n                    <jats:sub>50<\/jats:sub>\n                    values of 104, 117 and 134\u00a0\u03bcg\u00a0ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    , respectively, after 72\u00a0h.\n                    <jats:styled-content style=\"fixed-case\">IAA<\/jats:styled-content>\n                    is a well\u2010known phytohormone that plays a role in triggering plant resistance, thus suggesting a dual activity, either directly, by killing or compromising nematodes, or indirectly, by inducing defence mechanisms against pathogens (nematodes) in plants. Such compounds may serve as important leads in the development of novel, environmental friendly, nematocides.\n                  <\/jats:p>","DOI":"10.1111\/1751-7915.12467","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T04:46:44Z","timestamp":1482122804000},"page":"175-188","source":"Crossref","is-referenced-by-count":122,"title":["Bioactive secondary metabolites with multiple activities from a fungal endophyte"],"prefix":"10.1111","volume":"10","author":[{"given":"Catherine W.","family":"Bogner","sequence":"first","affiliation":[{"name":"Institute of Crop Science and Resource Conservation (INRES) Department of Molecular Phytomedicine University of Bonn Karlrobert\u2010Kreiten Str. 13 53115 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramsay S.T.","family":"Kamdem","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Biology and Biotechnology Heinrich\u2010Heine\u2010University D\u00fcsseldorf Universit\u00e4ts Str. 1. Building. 26.23 40225 D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisela","family":"Sichtermann","sequence":"additional","affiliation":[{"name":"Institute of Crop Science and Resource Conservation (INRES) Department of Molecular Phytomedicine University of Bonn Karlrobert\u2010Kreiten Str. 13 53115 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Matth\u00e4us","sequence":"additional","affiliation":[{"name":"Institute of Photonic Technology Workgroup Spectroscopy\/Imaging Albert\u2010Einstein\u2010Str. 9 07745 Jena Germany"},{"name":"Institute of Physical Chemistry and Abbe Center of Photonics Friedrich Schiller University Helmholtzweg 4 07743 Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"H\u00f6lscher","sequence":"additional","affiliation":[{"name":"Research Group Biosynthesis\/NMR Max Planck Institute for Chemical Ecology Hans\u2010Kn\u00f6ll\u2010Str. 8 07745 Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Popp","sequence":"additional","affiliation":[{"name":"Institute of Photonic Technology Workgroup Spectroscopy\/Imaging Albert\u2010Einstein\u2010Str. 9 07745 Jena Germany"},{"name":"Institute of Physical Chemistry and Abbe Center of Photonics Friedrich Schiller University Helmholtzweg 4 07743 Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Proksch","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Biology and Biotechnology Heinrich\u2010Heine\u2010University D\u00fcsseldorf Universit\u00e4ts Str. 1. Building. 26.23 40225 D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian M.W.","family":"Grundler","sequence":"additional","affiliation":[{"name":"Institute of Crop Science and Resource Conservation (INRES) Department of Molecular Phytomedicine University of Bonn Karlrobert\u2010Kreiten Str. 13 53115 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Schouten","sequence":"additional","affiliation":[{"name":"Institute of Crop Science and Resource Conservation (INRES) Department of Molecular Phytomedicine University of Bonn Karlrobert\u2010Kreiten Str. 13 53115 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(88)80051-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf3038874"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11557-016-1169-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.4.564"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10482-013-0095-y"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.2008.02508.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.1734"},{"key":"e_1_2_8_9_1","first-page":"475","article-title":"Influence of F. oxysporum, a mutualistic fungal endophyte, on M. incognita of tomato","volume":"101","author":"Hallmann J.","year":"1994","journal-title":"J Plant Dis Prot"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01877102"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00214-011-0957-1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R046094"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2015.04.010"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10535-007-0101-1"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf304314g"},{"key":"e_1_2_8_16_1","first-page":"163","article-title":"The fungal endophyte dilemma","volume":"33","author":"Hyde K.D.","year":"2008","journal-title":"Fungal Divers"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2008.03528.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/mpp.12057"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2015.130"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2014.6033"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.60.1375"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.D011940"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.5423\/PPJ.2007.23.4.318"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-017-8730-7_7"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2014.964713"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1079\/9780851997278.0000"},{"key":"e_1_2_8_27_1","first-page":"1693","article-title":"Bacillus thuringiensis (Bt) Toxin Susceptibility and Isolation of Resistance Mutants in the Nematode Caenorhabditis elegans","volume":"155","author":"Marroquin L.D.","year":"2000","journal-title":"GSA"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1094\/PHYTO-04-11-0120"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10526-012-9471-1"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-014-2237-5"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2003-4-4-r26"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.04.058"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2013.04.005"},{"key":"e_1_2_8_34_1","unstructured":"Office P. Commission Regulation (EU)(2011)No 186\/2011 of 25 February 2011 amending Annex I to Regulation (EC) No 689\/2008 of the European Parliament and of the Council concerning the export and import of dangerous chemicals."},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppa.12202"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1143409"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/np1008976"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-092910-154055"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/epp.12077"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2014.10.093"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.12.56"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-phyto-080615-100114"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1515\/znc-2010-3-407"},{"key":"e_1_2_8_44_1","first-page":"127","article-title":"The surface coat of plant\u2010parasitic nematodes: chemical composition, origin and biological role\u2010 A review","volume":"27","author":"Spiegel Y.","year":"1995","journal-title":"J Nematol"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3059.1997.d01-201.x"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2011.04.002"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0953-7562(09)81063-0"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1163\/156854106776179953"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.112.212597"}],"container-title":["Microbial Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1751-7915.12467","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sfamjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1751-7915.12467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T15:25:00Z","timestamp":1762269900000},"score":1,"resource":{"primary":{"URL":"https:\/\/sfamjournals.onlinelibrary.wiley.com\/doi\/10.1111\/1751-7915.12467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,19]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/1751-7915.12467"],"URL":"https:\/\/doi.org\/10.1111\/1751-7915.12467","archive":["Portico"],"relation":{},"ISSN":["1751-7915","1751-7915"],"issn-type":[{"value":"1751-7915","type":"print"},{"value":"1751-7915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,19]]}}}