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These latter strains are normally relatively resistant to bacteriocins, due to cell wall and cell membrane modifications. Genomic sequencing showed that the strain harboured at least two complete gene clusters for biosynthesis of antagonistic substances. The complete biosynthetic gene cluster of the well\u2010known lantibiotic gallidermin was encoded on a large plasmid and the mature peptide was present in isopropanol cell extracts. In addition, a chromosomal island contained a novel non\u2010ribosomal peptide synthetase (NRPS) gene cluster. Accidental deletion of two NRPS modules and partial purification of the anti\u2010VISA activity showed that this novel bacteriocin represents a complex of differently decorated, non\u2010ribosomal peptides. Additionally, a number of phenol\u2010soluble modulins (PSMs) was detected by mass spectrometry of whole cells. Producing these compounds, the strain was able to outcompete several\n                    <jats:italic>S. aureus<\/jats:italic>\n                    strains, including MRSA and VISA, in tube cultures.\n                  <\/jats:p>","DOI":"10.1111\/1751-7915.14356","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T10:23:54Z","timestamp":1697624634000},"page":"2181-2193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A\n                    <i>Staphylococcus capitis<\/i>\n                    strain with unusual bacteriocin production"],"prefix":"10.1111","volume":"16","author":[{"given":"Christiane","family":"Szekat","sequence":"first","affiliation":[{"name":"Institute of Medical Microbiology, Immunology and Parasitology University Hospital Bonn  Bonn 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