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Although bacteriophage\u2010based biocontrol has shown promise against Psc, no studies have examined phages targeting blueberry\u2010tropic Psc lineages. Here, we isolated phages infecting Psc strains from diseased highbush blueberry (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Vaccinium corymbosum<\/jats:italic>\n                    <\/jats:styled-content>\n                    ), and evaluated their suitability for biocontrol using a multi\u2010stage screening pipeline incorporating host\u2010range analysis, comparative genomics, environmental stability testing, in\u00a0vitro antibacterial efficacy assays and ex planta validation. Twelve of the isolated phages exhibited favourable host\u2010range characteristics. Genomic analyses revealed substantial phylogenetic diversity among these candidates but simultaneously identified multiple clonal groups, reducing the collection to eight non\u2010redundant phages spanning five distinct genera. Candidate phages generally retained infectivity under environmentally relevant conditions and exhibited heterogeneous but largely favourable stability profiles. Planktonic killing assays uncovered considerable variation in antibacterial efficacy, but phage performance appeared to be driven by infection compatibility and host\u2010specific factors rather than properties intrinsic to individual phages. Notably, the jumbo phage CB10 emerged as a particularly promising candidate due to its strong antibacterial activity (median GRC\u2009=\u20090.943), favourable environmental stability and unique genomic features. Cocktails containing the most effective candidates produced substantial and longitudinally sustained reductions in epiphytic colonization of detached blueberry leaves by Psc, exceeding five orders of magnitude at peak efficacy and demonstrating robust activity in a biologically relevant ex planta system. Importantly, in\u00a0vitro antibacterial efficacy was predictive of performance in our ex planta model (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.67;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0003), supporting the utility of tiered screening approaches for candidate selection. Taken together, these findings establish a framework for the systematic identification and evaluation of phages targeting Psc, and support the development of phage\u2010based interventions for managing plant diseases.\n                  <\/jats:p>","DOI":"10.1111\/1751-7915.70438","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:58:56Z","timestamp":1788933536000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bacteriophages Control Epiphytic\n                    <scp>\n                      <i>Pseudomonas syringae<\/i>\n                    <\/scp>\n                    Populations in Highbush Blueberry Leaves"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9065-2564","authenticated-orcid":false,"given":"Cassidy","family":"Ball","sequence":"first","affiliation":[{"name":"Faculty of Land and Food Systems The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7483-8488","authenticated-orcid":false,"given":"Philip","family":"Lauman","sequence":"additional","affiliation":[{"name":"Faculty of Land and Food Systems The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3829-8688","authenticated-orcid":false,"given":"Tongzhou","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Agricultural and Environmental Sciences University of Georgia  Griffin Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5549-3881","authenticated-orcid":false,"given":"Thomas","family":"Guy","sequence":"additional","affiliation":[{"name":"Summerland Research and Development Centre Agriculture &amp; Agri\u2010Food Canada  Summerland British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4607-506X","authenticated-orcid":false,"given":"Kasia","family":"Dadej","sequence":"additional","affiliation":[{"name":"Ottawa Research and Development Centre Agriculture &amp; Agri\u2010Food Canada  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1175-9130","authenticated-orcid":false,"given":"Robin","family":"Richter","sequence":"additional","affiliation":[{"name":"Ottawa Research and Development Centre Agriculture &amp; Agri\u2010Food Canada  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5923-6225","authenticated-orcid":false,"given":"Mark","family":"Lubberts","sequence":"additional","affiliation":[{"name":"Summerland Research and Development Centre Agriculture &amp; Agri\u2010Food Canada  Summerland British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8436-944X","authenticated-orcid":false,"given":"Keiran","family":"Cross","sequence":"additional","affiliation":[{"name":"Summerland Research and Development Centre Agriculture &amp; 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