{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:04:27Z","timestamp":1787061867256,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,5,8]],"date-time":"2014-05-08T00:00:00Z","timestamp":1399507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010724","name":"Health Systems Research Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010724","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100007261","name":"Bureau of Policy and Strategy, Ministry of Public Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007261","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100009061","name":"Thai Health Promotion Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009061","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Health Security Office, Thailand"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Epidemiological studies of the association between bisphenol\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      ) exposure and diabetes have been inconsistent. The present study determined serum\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      concentrations in the Thai population and their association with hyperglycemia and diabetes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In all, 2581 serum samples from the\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      hai\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      ational\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      ealth\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      xamination\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      urvey (2009) were used to determine\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      levels. Impaired fasting glucose (\n                      <jats:styled-content style=\"fixed-case\">IFG<\/jats:styled-content>\n                      ) was defined as fasting plasma glucose \u2265100 and &lt;126\u2009mg\/dL. Diabetes was defined as a history of a physician's diagnosis or fasting plasma glucose \u2265126\u2009mg\/dL. Multinomial logistic regression was used to examine the association of serum\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      with\n                      <jats:styled-content style=\"fixed-case\">IFG<\/jats:styled-content>\n                      and diabetes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 2581 samples tested,\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      was detected in 2135 samples (weighted percentage 78.1%), with a geometric mean concentration of 0.34\u2009ng\/mL\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      . Serum\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      levels were significantly higher among those with diabetes or\n                      <jats:styled-content style=\"fixed-case\">IFG<\/jats:styled-content>\n                      compared with normoglycemic individuals (0.52 and 0.38 vs 0.33\u2009ng\/mL, respectively;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). After adjusting for potential confounders, compared with the first quartile (\u22640.071\u2009ng\/mL), the overall adjusted odds ratios (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      ) of serum\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      concentration in the third and fourth quartiles (0.319\u20130.745 and \u22650.746\u2009ng\/mL, respectively) for\n                      <jats:styled-content style=\"fixed-case\">IFG<\/jats:styled-content>\n                      were 1.72 (95% confidence interval [\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ] 1.19, 2.49) and 1.23 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.80, 1.89), respectively; for diabetes, the adjusted\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      were 1.88 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.18, 2.99) and 1.83 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.12, 2.95), respectively, with a slightly stronger association among men than in women.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Serum\n                      <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content>\n                      concentrations were not associated with\n                      <jats:styled-content style=\"fixed-case\">IFG<\/jats:styled-content>\n                      , but were positively associated with diabetes in the\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      hai population. Further prospective studies are needed to confirm the relationship.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1753-0407.12159","type":"journal-article","created":{"date-parts":[[2014,4,11]],"date-time":"2014-04-11T04:12:52Z","timestamp":1397189572000},"page":"240-249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Relationship of serum bisphenol\n                    <scp>A<\/scp>\n                    with diabetes in the\n                    <scp>T<\/scp>\n                    hai population,\n                    <scp>N<\/scp>\n                    ational\n                    <scp>H<\/scp>\n                    ealth\n                    <scp>E<\/scp>\n                    xamination\n                    <scp>S<\/scp>\n                    urvey\n                    <scp>IV<\/scp>\n                    , 2009 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