{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T22:59:21Z","timestamp":1769813961326,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T00:00:00Z","timestamp":1482364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Alzheimer Disease Research Center at Mount Sinai","award":["U01 P50 AG005138"],"award-info":[{"award-number":["U01 P50 AG005138"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2017,10]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Diabetes mellitus is a risk factor for cognitive changes, but assessment for cognitive disorders in this population is performed infrequently. The present study examined the frequency of cognitive disorders and patterns of deficit in patients enrolled in a specialized clinic for diabetes.<\/jats:p><\/jats:sec>Methods<\/jats:title>A cross\u2010sectional study was conducted to assess cognition in M<\/jats:styled-content>ount S<\/jats:styled-content>inai D<\/jats:styled-content>iabetes C<\/jats:styled-content>enter patients. Thirty eligible subjects aged \u226550\u2009years were assessed and compared with non\u2010diabetic cognitively normal control subjects, as well as non\u2010diabetic subjects with mild cognitive impairment (MCI<\/jats:styled-content>). The main outcome(s) and measure(s) were obtained through cognitive assessment and diagnosis using the A<\/jats:styled-content>lzheimer's D<\/jats:styled-content>isease C<\/jats:styled-content>enters\u2019 uniform data set.<\/jats:p><\/jats:sec>Results<\/jats:title>Forty percent of subjects were newly diagnosed with a cognitive disorder: 10% were diagnosed with dementia and 30% with MCI<\/jats:styled-content>. Diabetic subjects performed worse on the M<\/jats:styled-content>ini\u2010M<\/jats:styled-content>ental S<\/jats:styled-content>tate E<\/jats:styled-content>xamination (27.2 vs 28.4; P<\/jats:italic>\u2009=\u20090.0132), list generation (9.5 vs 12.2; P<\/jats:italic>\u2009=\u20090.0190), T<\/jats:styled-content>rail M<\/jats:styled-content>aking T<\/jats:styled-content>est, P<\/jats:styled-content>arts A<\/jats:styled-content> (70.1 vs 43.0; P<\/jats:italic>\u2009< 0.0001) and B<\/jats:styled-content> (197.2 vs 123.6; P<\/jats:italic>\u2009< 0.0001), and the D<\/jats:styled-content>igit S<\/jats:styled-content>ymbol test (12.7 vs 40.1; P<\/jats:italic>\u2009< 0.0001) than cognitively normal individuals. Compared with subjects with MCI<\/jats:styled-content> (amnestic type), diabetic subjects performed better on tasks of immediate and delayed recall (11.2 vs 7.3 [P<\/jats:italic>\u2009=\u20090.0048] and 8.4 vs. 4.1 [P<\/jats:italic>\u2009=\u20090.0003], respectively).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Undiagnosed cognitive disorders are common and underappreciated in patients being treated in a specialized diabetes clinic. It may be important to make cognitive assessment a standard part of patient assessments.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.12503","type":"journal-article","created":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T07:13:31Z","timestamp":1478157211000},"page":"929-935","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Cognitive performance of older adults in a specialized diabetes clinic"],"prefix":"10.1111","volume":"9","author":[{"given":"Corbett","family":"Schimming","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Alzheimer's Disease Research Center Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"James J. Peters VA Medical Center New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodong","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Alzheimer's Disease Research Center Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"James J. Peters VA Medical Center New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Sano","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Alzheimer's Disease Research Center Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"James J. Peters VA Medical Center New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,22]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"National Diabetes Fact Sheet: National Estimates and General Information on Diabetes and Prediabetes in the United States, 2011","author":"Centers for Disease Control and Prevention (CDC)","year":"2011"},{"key":"e_1_2_7_3_1","unstructured":"International Diabetes Federation (IDF).Diabetes Atlas. Available from:http:\/\/www.idf.org\/diabetesatlas(accessed 11 July 2016)."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2004.02.054"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70284-2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2012.02758.x"},{"key":"e_1_2_7_7_1","first-page":"293","article-title":"Glycosylated hemoglobin level and development of mild cognitive impairment or dementia in older women","volume":"10","author":"Yaffe K","year":"2006","journal-title":"J Nutr Health Aging"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2008.02.048"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38446.466238.E0"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000140292.04932.87"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.4.471"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-1637"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70005-4"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa066397"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.10.028"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70188-0"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wad.0000213866.86934.7e"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2007.29"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000279520.59792.fe"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e32816ebc7b"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70249-2"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.5.661"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.233"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000324925.95210.6d"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000064928"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2013.01.001"}],"container-title":["Journal of Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1753-0407.12503","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1753-0407.12503","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1753-0407.12503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:12:44Z","timestamp":1695474764000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1753-0407.12503"}},"subtitle":["\u5c31\u8bca\u4e8e\u7cd6\u5c3f\u75c5\u4e13\u79d1\u95e8\u8bca\u7684\u8001\u5e74\u4eba\u8ba4\u77e5\u8868\u73b0"],"short-title":[],"issued":{"date-parts":[[2016,12,22]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/1753-0407.12503"],"URL":"https:\/\/doi.org\/10.1111\/1753-0407.12503","archive":["Portico"],"relation":{},"ISSN":["1753-0393","1753-0407"],"issn-type":[{"value":"1753-0393","type":"print"},{"value":"1753-0407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,22]]},"assertion":[{"value":"2016-05-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}