{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T07:48:39Z","timestamp":1744271319393},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T00:00:00Z","timestamp":1499990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Centre European d\u2019Etude du Diabetes (Strasbourg, France)"},{"name":"M\u00e9decins Sans Fronti\u00e8res (Belgium)"},{"name":"Servier International offices in Paris and Phnom Penh"},{"name":"WHO national and regional offices"},{"name":"International Diabetes Federation"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Despite growing attention to diabetes throughout <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>sia, data from <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>outheast <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>sia are limited. This article reports rates of diabetes, hypertension, and obesity in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ambodia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two studies were conducted across different regions of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ambodia: (i) a 2012 screening study across urban, semi\u2010urban, and rural areas that used point\u2010of\u2010care capillary glucose for determination of diabetes (<jats:italic>n<\/jats:italic>\u2009<jats:italic>=<\/jats:italic>\u200913\u2009997); and (ii) a 2005 epidemiological study with random selection from two main urban areas that used oral glucose tolerance tests for determination of diabetes (<jats:italic>n<\/jats:italic>\u2009<jats:italic>=<\/jats:italic>\u20091863). Blood pressure and anthropometrics were also measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the screening study, rates of diabetes were significantly higher in urban than rural sites, with intermediate rates in semi\u2010urban areas. There was a significant dose\u2013response effect for urbanicity on overweight, obesity, and waist:hip ratio, with higher rates for urban versus semi\u2010urban and for semi\u2010urban versus rural locales. Rural sites had the lowest rates of hypertension, followed by urban and semi\u2010urban sites. Among people who screened positive for diabetes, there was a dose\u2013response effect for urbanicity on undiagnosed diabetes; rates of previously undiagnosed diabetes were lowest in urban (51%), followed by semi\u2010urban (55%) and rural (67%) locales. Rural participants reported the highest rates of smoking and alcohol use. In the urban epidemiological study, prevalence rates of diabetes and impaired glucose tolerance were approximately 10%, indicating a prevalence of total glucose intolerance of approximately 20%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ambodia, diabetes rates are high among urban residents and undiagnosed diabetes is highest among rural residents. A country\u2010wide public health response is urgently needed; as development continues, rates of diabetes are expected to rise.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.12570","type":"journal-article","created":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T00:24:41Z","timestamp":1495585481000},"page":"148-157","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Diabetes and cardiometabolic risk factors in <scp>C<\/scp>ambodia: <scp>R<\/scp>esults from two screening studies"],"prefix":"10.1111","volume":"10","author":[{"given":"Julie","family":"Wagner","sequence":"first","affiliation":[{"name":"Department of Behavioral Sciences and Community Health University of Connecticut Schools of Medicine and Dental Medicine  Farmington Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Naranjo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics \u2010 Endocrinology and Diabetes Stanford University School of Medicine  Palo Alto California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Touch","family":"Khun","sequence":"additional","affiliation":[{"name":"Cambodian Diabetes Association  Siem Reap Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serey","family":"Seng","sequence":"additional","affiliation":[{"name":"Cambodian Diabetes Association  Siem Reap Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ien S.","family":"Horn","sequence":"additional","affiliation":[{"name":"Cambodian Diabetes Association  Siem Reap Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakinah C.","family":"Suttiratana","sequence":"additional","affiliation":[{"name":"Department of Pediatrics \u2010 Endocrinology and Diabetes Stanford University School of Medicine  Palo Alto California USA"},{"name":"Department of Social and Behavioral Sciences University of California, San Francisco  San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lim","family":"Keuky","sequence":"additional","affiliation":[{"name":"Cambodian Diabetes Association  Siem Reap Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Diabetes Atlas","author":"International Diabetes Federation (IDF)","year":"2015"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2011.10.029"},{"key":"e_1_2_7_4_1","unstructured":"The World Bank.Cambodia.2015. 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